Nettsider med emneord «brain research»
We show that systemic injections of PHP.eB AAVs to express GECIs is a highly promising technique for imaging neural activity and circumvent the need for transgenic GECI expressing mouse lines. We also establish the use of novel soma-targeted GECIs that outperform current Ca2+ indicators using both systemic and local virus injections.
This is a project in collaboration with the Hafting-Fyhn group at the institute for biological sciences (IBV) at the biology department. The goal is to construct a neural recording device that records neural signals from a rat for several hours form brain electrodes onto a memory card. The system needs to be compact and light enough to be carried by the animal.
This is a project in collaboration with the Hafting-Fyhn group at the institute for biological sciences (IBV) at the biology department. The goal is to construct a neural recording device that records neural signals from a rat for several hours form brain electrodes onto a memory card. The system needs to be compact and light enough to be carried by the animal. There are two variants on how to approach this system: either 1) a fully integrated system (except for the memory card) on an integrated circuit or 2) as system built from a commercial neural amplifier and analog to digital converter chip (e.g. from Intan AS) and an FPGA that controls this chip and interfaces it with a memory card.
Wireless solutions in brain research have so far been limited
by low data transmission, short recording time or bulky batteries and devices. Our objective is to develop a wireless Micro Electro-Optical system (MEMS) device for long-term, recording and manipulations of brain activity in rodents.