Although “Big Pharma” has in general moved away from Natural Products (NP) as a source of drug leads or drugs themselves, the published record demonstrates that over the last 30 years NP structures or modified structures are still major sources of drugs against a variety of diseases.
This seminar will cover some history but will demonstrate how even in the “age of combi-chem”, NP structures and the “Chemical DNA of those structures” is still utilized in drug discovery.