Following the Rosseland Centre for Solar Physics, the Hylleraas Centre is the second biggest user of computing power in the national infrastructure for computational science in Norway managed by UNINETT Sigma2 AS. In an interview in Titan.uio.no, Hylleraas Director Trygve Helgaker and Professor Stian Svelle at the Department of Chemistry explain why computing and simulation has become an indispensable tool in nearly all of chemistry.