Malgorzata Elzbieta Zawadzka

• Zawadzka, Malgorzata Elzbieta; Racz, Beatrix; Ambrosini, Dario; Görbitz, Carl Henrik; Morth, Jens Preben & Wilkins, Alistair L. [Show all 12 contributors for this article] (2021). Searching for a UV-filter in the eyes of high-flying birds. Scientific Reports. ISSN 2045-2322. 11(1). doi: 10.1038/s41598-020-79533-2. Full text in Research Archive
• Ihlefeldt, Franziska Stefanie; Pettersen, Fredrik; von Bonin, Aidan; Zawadzka, Malgorzata Elzbieta & Gorbitz, Carl Henrik (2014). The polymorphs of L-phenylalanine. Angewandte Chemie International Edition. ISSN 1433-7851. 53(49), p. 13600–13604. doi: 10.1002/anie.201406886.

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• Haavaag, Jon Erlend; Kogler, Stian; Zawadzka, Malgorzata Elzbieta; Krauss, Stefan Johannes Karl; Wilson, Steven Ray Haakon & Røberg-Larsen, Hanne (2023). Building a high-resolution nano DESI-MS for organoid imaging: Analysis using a built and optimized imaging system.
• Racz, Beatrix; Zawadzka, Malgorzata Elzbieta; Skytte Af Sätra, Jenny Marie; Ringvold, Amund; Rise, Frode & Lundanes, Elsa [Show all 7 contributors for this article] (2018). Identification of “compound X” in goose aqueous humour.
• Zawadzka, Malgorzata Elzbieta; Wilson, Steven Ray Haakon & Görbitz, Carl Henrik (2016). Unravelling nature s sunglasses – Identifying the compound that protects bird eyes. Universitetet i Oslo. Show summary

  Ultraviolet (UV) protection is crucial for all living organisms as it can cause serious harm damaging the DNA of cells and leading to conditions such as cataracts, blindness and skin cancer. Many animals can either produce their own sunscreen compound or acquire it in their diet. Goose eyes contain a single, unknown component (“Compound X”) that dominates the UV absorbing profile of the goose eye chamber fluid and with its high absorbance functions as natural sunglasses for geese. The aim of this study was to identify “Compound X” using various established analytical techniques and methods, as well as develop a new one; the concept of temperature programming crystallization prior to single crystal X-ray diffractometric analysis for limited samples was explored. High performance liquid chromatography (HPLC)-UV analysis confirmed the presence of a single compound with a maximum absorption of 254 nm, implying the presence of an aromatic ring. MS analysis implied a molar mass of 149.05 g/mol, and presence of hydroxyl group and carbon chain containing methyl group. As the “Compound X” crystallized in the form of fibers, it was not possible to conduct single crystal X-ray diffraction (SCXRD) analysis on the available diffractometer. When using model compounds, crystals obtained with temperature programming were suitable for SCXRD analysis. Further experimentation with this technique may open possibilities for structure elucidation of the “Compound X” and other new compounds in small samples.

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