News
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Network with over a million human genomes becomes available for research Nov. 18, 2022 3:23 PM
In the long term, this could have a major impact on personalized medicine.
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Bacterial genes in the faeces can reveal early colorectal cancer Nov. 18, 2022 1:12 PM
Scientists are now analysing all the genes in the intestinal content of thousands of people. The aim is to reveal the early phase of colorectal cancer by looking at the microbiota in the bowel.
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New group leader at the Centre for Bioinformatics May 20, 2022 9:18 AM
The centre for Bioinformatics is delighted to announce that Dr. Trine Rounge has started as a new group leader at the centre from May 2022. Rounge group aims to unravel the molecular mechanisms that can detect and explain cancer progression at an early stage.
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MoDLE: High-performance stochastic modeling of DNA loop extrusion interactions Apr. 28, 2022 9:21 PM
"MoDLE is a computational tool for fast, stochastic modeling of molecular contacts from DNA loop extrusion capable of simulating realistic contact patterns genome wide in a few minutes. MoDLE accurately simulates contact maps in concordance with existing molecular dynamics approaches and with Micro-C data, and does so orders of magnitude faster than existing approaches. MoDLE's speed opens up for exploratory and predictive modeling of 3D genome structure in a wide range of settings", says Jonas Paulsen, professor at the Department of Biosciences.
Sven Furberg Seminars in Bioinformatics and Statistical Genomics
The latest publications from the Centre
Hictk: blazing fast toolkit to work with .hic and .cool files
Bioinformatics (in press)
DOI 10.1093/bioinformatics/btae408, PubMed 38913844
Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components
Cereb Cortex, 34 (6)
DOI 10.1093/cercor/bhae234, PubMed 38850213
Linguistics-based formalization of the antibody language as a basis for antibody language models
Nat Comput Sci, 4 (6), 412-422
DOI 10.1038/s43588-024-00642-3, PubMed 38877120
Software developed at the centre
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CARMA
Software for extraction of DNA copy number motifs in cancer
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Chimeraviz
Chimeraviz manages data from fusion gene finders and provides useful visualization tools.
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CompAIRR
Comparison of Adaptive Immune Receptor Repertoires
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Genomic HyperBrowser
Statistical methodology and computing power to handle a variety of biological inquires on genomic datasets
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HoCoRT
Host contamination removal tool
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immuneML
immuneML: an ecosystem for machine learning analysis of adaptive immune receptor repertoires
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KAGE
Kmer-based Alignment-free Graph Genotyper
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MoDLE
MoDLE: High-performance stochastic modeling of DNA loop extrusion interactions
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ScaR
ScaR — a tool for sensitive detection of known fusion transcripts: establishing prevalence of fusions in testicular germ cell tumors
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Swarm
Highly-scalable and high-resolution amplicon clustering
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VSEARCH
A versatile open source tool for metagenomics
Collaborations
ELIXIR Norway
ELIXIR Norway is the Norwegian national node of ELIXIR, the pan-European infrastructure for biological information, supporting life science research and its translation to medicine, environment, the bioindustries and society. This organization is a virtual organization where the Center of Bioinformatics hosts the regional Oslo node. It participates to the national help-desk user support, and in that activity also collaborates and coordinates closely with the Helse Sør-Øst-funded Bioinformatics Core facility.
Partners and collaborating organizational units
