Publications

Publications 2024

Lund-Andersen C, Torgunrud A, Kanduri C, Dagenborg VJ, Frøysnes IS, Larsen MM, Davidson B, Larsen SG, Flatmark K (2024)
Novel drug resistance mechanisms and drug targets in BRAF-mutated peritoneal metastasis from colorectal cancer
J Transl Med, 22 (1), 646
DOI 10.1186/s12967-024-05467-2, PubMed 38982444

Senthakumaran T, Tannæs TM, Moen AEF, Brackmann SA, Jahanlu D, Rounge TB, Bemanian V, Tunsjø HS (2024)
Detection of colorectal-cancer-associated bacterial taxa in fecal samples using next-generation sequencing and 19 newly established qPCR assays
Mol Oncol (in press)
DOI 10.1002/1878-0261.13700, PubMed 38970464

Wootton O, Shadrin AA, Bjella T, Smeland OB, van der Meer D, Frei O, O'Connell KS, Ueland T, Andreassen OA, Stein DJ, Dalvie S (2024)
Genomic insights into the shared and distinct genetic architecture of cognitive function and schizophrenia
Sci Rep, 14 (1), 15356
DOI 10.1038/s41598-024-66085-y, PubMed 38961113

Cyll K, Skaaheim Haug E, Pradhan M, Vlatkovic L, Carlsen B, Löffeler S, Kildal W, Skogstad K, Hauge Torkelsen F, Syvertsen RA, Askautrud HA, Liestøl K, Kleppe A, Danielsen HE (2024)
DNA ploidy and PTEN as biomarkers for predicting aggressive disease in prostate cancer patients under active surveillance
Br J Cancer (in press)
DOI 10.1038/s41416-024-02780-x, PubMed 38961192

Rossini R, Paulsen J (2024)
hictk: blazing fast toolkit to work with .hic and .cool files
Bioinformatics, 40 (7)
DOI 10.1093/bioinformatics/btae408, PubMed 38913844

Bogaard M, Strømme JM, Kidd SG, Johannessen B, Bakken AC, Lothe RA, Axcrona K, Skotheim RI, Axcrona U (2024)
GRIN3A: A biomarker associated with a cribriform pattern and poor prognosis in prostate cancer
Neoplasia, 55, 101023
DOI 10.1016/j.neo.2024.101023, PubMed 38944914

Stawiski K, Fortner RT, Pestarino L, Umu SU, Kaaks R, Rounge TB, Elias KM, Fendler W, Langseth H (2024)
Validation of miRNA signatures for ovarian cancer earlier detection in the pre-diagnosis setting using machine learning approaches
Front Oncol, 14, 1389066
DOI 10.3389/fonc.2024.1389066, PubMed 38983926

Smith DM, Parekh P, Kennedy J, Loughnan R, Frei O, Nichols TE, Andreassen OA, Jernigan TL, Dale AM (2024)
Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components
Cereb Cortex, 34 (6)
DOI 10.1093/cercor/bhae234, PubMed 38850213

Vu MH, Robert PA, Akbar R, Swiatczak B, Sandve GK, Haug DTT, Greiff V (2024)
Linguistics-based formalization of the antibody language as a basis for antibody language models
Nat Comput Sci, 4 (6), 412-422
DOI 10.1038/s43588-024-00642-3, PubMed 38877120

Frei O, Hindley G, Shadrin AA, van der Meer D, Akdeniz BC, Hagen E, Cheng W, O'Connell KS, Bahrami S, Parker N, Smeland OB, Holland D, Schizophrenia Working Group of the Psychiatric Genomics Consortium, de Leeuw C, Posthuma D, Andreassen OA, Dale AM (2024)
Improved functional mapping of complex trait heritability with GSA-MiXeR implicates biologically specific gene sets
Nat Genet, 56 (6), 1310-1318
DOI 10.1038/s41588-024-01771-1, PubMed 38831010

Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2024)
Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology
Neurol Genet, 10 (3), e200143
DOI 10.1212/NXG.0000000000200143, PubMed 38817246

Yang M, Kaarbø M, Myhre V, Reims HM, Karlsen TH, Wang J, Rognes T, Halvorsen B, Fevang B, Lundin KEA, Aukrust P, Bjørås M, Jørgensen SF (2024)
Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients
J Clin Immunol, 44 (6), 133
DOI 10.1007/s10875-024-01726-5, PubMed 38780872

Shahrouzi P, Forouz F, Mathelier A, Kristensen VN, Duijf PHG (2024)
Copy number alterations: a catastrophic orchestration of the breast cancer genome
Trends Mol Med (in press)
DOI 10.1016/j.molmed.2024.04.017, PubMed 38772764

Reppe S, Gundersen S, Sandve GK, Wang Y, Andreassen OA, Medina-Gomez C, Rivadeneira F, Utheim TP, Hovig E, Gautvik KM (2024)
Identification of Transcripts with Shared Roles in the Pathogenesis of Postmenopausal Osteoporosis and Cardiovascular Disease
Int J Mol Sci, 25 (10)
DOI 10.3390/ijms25105554, PubMed 38791593

Møller P, Haupt S, Ahadova A, Kloor M, Sampson JR, Sunde L, Seppälä T, Burn J, Bernstein I, Capella G, Evans DG, Lindblom A, Winship I, Macrae F, Katz L, Laish I, Vainer E, Monahan K, Half E, Horisberger K, da Silva LA, Heuveline V, Therkildsen C, Lautrup C, Klarskov LL et al. (2024)
Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated "Big Bang" pathway to CRC in three of the four Lynch syndromes
Hered Cancer Clin Pract, 22 (1), 6
DOI 10.1186/s13053-024-00279-3, PubMed 38741120

Rostami S, Rounge TB, Pestarino L, Lyle R, Fortner RT, Haaland ØA, Lie RT, Wiklund F, Bjørge T, Langseth H (2024)
Differential levels of circulating RNAs prior to endometrial cancer diagnosis
Int J Cancer, 155 (5), 946-956
DOI 10.1002/ijc.34951, PubMed 38733362

Akdeniz BC, Frei O, Hagen E, Filiz TT, Karthikeyan S, Pasman J, Jangmo A, Bergstedt J, Shorter JR, Zetterberg R, Meijsen J, Sønderby IE, Buil A, Tesli M, Lu Y, Sullivan P, Andreassen OA, Hovig E (2024)
COSGAP: COntainerized Statistical Genetics Analysis Pipelines
Bioinform Adv, 4 (1), vbae067
DOI 10.1093/bioadv/vbae067, PubMed 38808072

Halvorsen LV, Søraas CL, Larstorp ACK, Hjørnholm U, Kjær VN, Liestøl K, Aune A, Olsen E, Brobak KM, Bergland OU, Rognstad S, Aarskog NR, Heimark S, Fadl Elmula FEM, Gerdts E, Mo R, Solbu MD, Opdal MS, Kjeldsen SE, Rostrup M, Høieggen A (2024)
Effect of Drug Monitoring on Adherence and Blood Pressure: A Multicenter Randomized Clinical Trial
Am J Hypertens (in press)
DOI 10.1093/ajh/hpae059, PubMed 38713475

Stålberg SM, Silwal-Pandit L, Bastani NE, Nebdal DJH, Lingjærde OC, Skålhegg BS, Kure EH (2024)
Preoperative profiles of plasma amino acids and derivatives distinguish periampullary cancer and benign disease
BMC Cancer, 24 (1), 555
DOI 10.1186/s12885-024-12320-8, PubMed 38702616

Edsjö A, Russnes HG, Lehtiö J, Tamborero D, Hovig E, Stenzinger A, Rosenquist R, PCM4EU consortium (2024)
High-throughput molecular assays for inclusion in personalised oncology trials - State-of-the-art and beyond
J Intern Med, 295 (6), 785-803
DOI 10.1111/joim.13785, PubMed 38698538

Lång E, Lång A, Blicher P, Rognes T, Dommersnes PG, Bøe SO (2024)
Topology-guided polar ordering of collective cell migration
Sci Adv, 10 (16), eadk4825
DOI 10.1126/sciadv.adk4825, PubMed 38630812

Tesfaye M, Jaholkowski P, Shadrin AA, van der Meer D, Hindley GFL, Holen B, Parker N, Parekh P, Birkenæs V, Rahman Z, Bahrami S, Kutrolli G, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA (2024)
Identification of Novel Genomic Loci for Anxiety and Extensive Genetic Overlap with Psychiatric Disorders
medRxiv
DOI 10.1101/2023.09.01.23294920, PubMed 37693403

Minotto T, Robert PA, Hobæk Haff I, Sandve GK (2024)
Assessing the feasibility of statistical inference using synthetic antibody-antigen datasets
Stat Appl Genet Mol Biol, 23 (1)
DOI 10.1515/sagmb-2023-0027, PubMed 38563699

Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Ueland T, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2024)
Unraveling the shared genetics of common epilepsies and general cognitive ability
medRxiv
DOI 10.1101/2024.03.25.24304773, PubMed 38585944

Johansen A, Sandve GKF, Ibsen JH, Lundin KEA, Sollid LM, Stamnaes J (2024)
Biopsy Proteome Scoring to Determine Mucosal Remodeling in Celiac Disease
Gastroenterology (in press)
DOI 10.1053/j.gastro.2024.03.006, PubMed 38467384

Nikolski M, Hovig E, Al-Shahrour F, Blomberg N, Scollen S, Valencia A, Saunders G (2024)
Roadmap for a European cancer data management and precision medicine infrastructure
Nat Cancer, 5 (3), 367-372
DOI 10.1038/s43018-023-00717-6, PubMed 38321342

Istvan P, Birkeland E, Avershina E, Kværner AS, Bemanian V, Pardini B, Tarallo S, de Vos WM, Rognes T, Berstad P, Rounge TB (2024)
Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
Nat Commun, 15 (1), 1791
DOI 10.1038/s41467-024-46033-0, PubMed 38424056

Shadrin AA, Hindley G, Hagen E, Parker N, Tesfaye M, Jaholkowski P, Rahman Z, Kutrolli G, Fominykh V, Djurovic S, Smeland OB, O'Connell KS, van der Meer D, Frei O, Andreassen OA, Dale AM (2024)
Dissecting the genetic overlap between three complex phenotypes with trivariate MiXeR
medRxiv
DOI 10.1101/2024.02.23.24303236, PubMed 38464132

Moreira-Soares M, Mossmann E, Travasso RDM, Bordin JR (2024)
TrajPy: empowering feature engineering for trajectory analysis across domains
Bioinform Adv, 4 (1), vbae026
DOI 10.1093/bioadv/vbae026, PubMed 38645716

Hindley G, Drange OK, Lin A, Kutrolli G, Shadrin AA, Parker N, O'Connell KS, Rødevand L, Cheng W, Bahrami S, Karadag N, Holen B, Jaholkowski P, Woldeyohannes MT, Djurovic S, Dale AM, Frei O, Ueland T, Smeland OB, Andreassen OA (2024)
Corrigendum to "Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders" [Psychoneuroendocrinology 157 (2023) 106368]
Psychoneuroendocrinology, 162, 106980
DOI 10.1016/j.psyneuen.2024.106980, PubMed 38336601

Parekh P, Fan CC, Frei O, Palmer CE, Smith DM, Makowski C, Iversen JR, Pecheva D, Holland D, Loughnan R, Nedelec P, Thompson WK, Hagler DJ, Andreassen OA, Jernigan TL, Nichols TE, Dale AM (2024)
FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data
Hum Brain Mapp, 45 (2), e26579
DOI 10.1002/hbm.26579, PubMed 38339910

Skotheim RI, Bogaard M, Carm KT, Axcrona U, Axcrona K (2024)
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature
Biochim Biophys Acta Rev Cancer, 1879 (2), 189080
DOI 10.1016/j.bbcan.2024.189080, PubMed 38272101

Andresen NK, Røssevold AH, Quaghebeur C, Gilje B, Boge B, Gombos A, Falk RS, Mathiesen RR, Julsrud L, Garred Ø, Russnes HG, Lereim RR, Chauhan SK, Lingjærde OC, Dunn C, Naume B, Kyte JA (2024)
Ipilimumab and nivolumab combined with anthracycline-based chemotherapy in metastatic hormone receptor-positive breast cancer: a randomized phase 2b trial
J Immunother Cancer, 12 (1)
DOI 10.1136/jitc-2023-007990, PubMed 38242720

Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Chèneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A (2024)
JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
Nucleic Acids Res, 52 (D1), D174-D182
DOI 10.1093/nar/gkad1059, PubMed 37962376

Sveen A, Johannessen B, Klokkerud SM, Kraggerud SM, Meza-Zepeda LA, Bjørnslett M, Bischof K, Myklebost O, Taskén K, Skotheim RI, Dørum A, Davidson B, Lothe RA (2024)
Evolutionary mode and timing of dissemination of high-grade serous carcinomas
JCI Insight, 9 (3)
DOI 10.1172/jci.insight.170423, PubMed 38175731

Bergstedt J, Pasman JA, Ma Z, Harder A, Yao S, Parker N, Treur JL, Smit DJA, Frei O, Shadrin AA, Meijsen JJ, Shen Q, Hägg S, Tornvall P, Buil A, Werge T, Hjerling-Leffler J, Als TD, Børglum AD, Lewis CM, McIntosh AM, Valdimarsdóttir UA, Andreassen OA, Sullivan PF, Lu Y et al. (2024)
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease
Nat Cardiovasc Res, 3 (6), 754-769
DOI 10.1038/s44161-024-00488-y, PubMed 38898929

Publications 2023

Billingham L, Brown L, Framke T, Greystoke A, Hovig E, Mathur S, Page P, Pean E, Barjesteh van Waalwijk van Doorn-Khosrovani S, Vonk R, Wissink S, Zander H, Plummer R (2023)
Histology independent drug development - Is this the future for cancer drugs?
Cancer Treat Rev, 123, 102674
DOI 10.1016/j.ctrv.2023.102674, PubMed 38176220

Icick R, Shadrin A, Holen B, Karadag N, Parker N, O'Connell K, Frei O, Bahrami S, Høegh M, Lagerberg T, Cheng W, Seibert T, Djurovic S, Dale A, Zhou H, Edenberg H, Gelernter J, Smeland O, Hindley G, Andreassen O (2023)
Identification of Novel Loci and Cross-Disorder Pleiotropy Through Multi-Ancestry Genome-Wide Analysis of Alcohol Use Disorder in Over One Million Individuals
Res Sq
DOI 10.21203/rs.3.rs-3755915/v1, PubMed 38196616

Shakibfar S, Zhao J, Li H, Nordeng H, Lupattelli A, Pavlovic M, Sandve GK, Nyberg F, Wettermark B, Hajiebrahimi M, Andersen M, Sessa M (2023)
Machine learning-driven development of a disease risk score for COVID-19 hospitalization and mortality: a Swedish and Norwegian register-based study
Front Public Health, 11, 1258840
DOI 10.3389/fpubh.2023.1258840, PubMed 38146473

Ølnes ÅS, Teigen M, Laerdahl JK, Leren TP, Strøm TB, Bjune K (2023)
Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP
PLoS One, 18 (12), e0294764
DOI 10.1371/journal.pone.0294764, PubMed 38039300

Jaholkowski P, Hindley GFL, Shadrin AA, Tesfaye M, Bahrami S, Nerhus M, Rahman Z, O'Connell KS, Holen B, Parker N, Cheng W, Lin A, Rødevand L, Karadag N, Frei O, Djurovic S, Dale AM, Smeland OB, Andreassen OA (2023)
Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci
Schizophr Bull, 49 (6), 1654-1664
DOI 10.1093/schbul/sbad063, PubMed 37163672

Rossini R, Oshaghi M, Nekrasov M, Bellanger A, Domaschenz R, Dijkwel Y, Abdelhalim M, Collas P, Tremethick D, Paulsen J (2023)
Multi-level 3D genome organization deteriorates during breast cancer progression
bioRxiv
DOI 10.1101/2023.11.26.568711, PubMed 38076897

Neves A, Cuesta I, Hjerde E, Klemetsen T, Salgado D, van Helden J, Rahman N, Fatima N, Karathanasis N, Zmora P, Åkerström WN, Grellscheid SN, Waheed Z, Blomberg N (2023)
FAIR+E pathogen data for surveillance and research: lessons from COVID-19
Front Public Health, 11, 1289945
DOI 10.3389/fpubh.2023.1289945, PubMed 38074768

Wootton O, Shadrin AA, Bjella T, Smeland OB, van der Meer D, Frei O, O'Connell KS, Ueland T, Andreassen OA, Stein DJ, Dalvie S (2023)
Genomic Insights into the Shared and Distinct Genetic Architecture of Cognitive Function and Schizophrenia
medRxiv
DOI 10.1101/2023.11.13.23298348, PubMed 38014326

Wæhler HA, Labba NA, Paulsen RE, Sandve GK, Eskeland R (2023)
ANDA: an open-source tool for automated image analysis of in vitro neuronal cells
BMC Neurosci, 24 (1), 56
DOI 10.1186/s12868-023-00826-z, PubMed 37875799

Høland M, Berg KCG, Eilertsen IA, Bjerkehagen B, Kolberg M, Boye K, Lingjærde OC, Guren TK, Mandahl N, van den Berg E, Palmerini E, Smeland S, Picci P, Mertens F, Sveen A, Lothe RA (2023)
Transcriptomic subtyping of malignant peripheral nerve sheath tumours highlights immune signatures, genomic profiles, patient survival and therapeutic targets
EBioMedicine, 97, 104829
DOI 10.1016/j.ebiom.2023.104829, PubMed 37837931

Møller P, Seppälä TT, Ahadova A, Crosbie EJ, Holinski-Feder E, Scott R, Haupt S, Möslein G, Winship I, Broeke SWB, Kohut KE, Ryan N, Bauerfeind P, Thomas LE, Evans DG, Aretz S, Sijmons RH, Half E, Heinimann K, Horisberger K, Monahan K, Engel C, Cavestro GM, Fruscio R, Abu-Freha N et al. (2023)
Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement
Hered Cancer Clin Pract, 21 (1), 19
DOI 10.1186/s13053-023-00263-3, PubMed 37821984

Reinar WB, Tørresen OK, Nederbragt AJ, Matschiner M, Jentoft S, Jakobsen KS (2023)
Teleost genomic repeat landscapes in light of diversification rates and ecology
Mob DNA, 14 (1), 14
DOI 10.1186/s13100-023-00302-9, PubMed 37789366

Birkeland E, Ferrero G, Pardini B, Umu SU, Tarallo S, Bulfamante S, Hoff G, Senore C, Rounge TB, Naccarati A (2023)
Profiling small RNAs in fecal immunochemical tests: is it possible?
Mol Cancer, 22 (1), 161
DOI 10.1186/s12943-023-01869-w, PubMed 37789383

Hsieh PH, Lopes-Ramos CM, Zucknick M, Sandve GK, Glass K, Kuijjer ML (2023)
Adjustment of spurious correlations in co-expression measurements from RNA-Sequencing data
Bioinformatics, 39 (10)
DOI 10.1093/bioinformatics/btad610, PubMed 37802917

Rumbavicius I, Rounge TB, Rognes T (2023)
HoCoRT: host contamination removal tool
BMC Bioinformatics, 24 (1), 371
DOI 10.1186/s12859-023-05492-w, PubMed 37784008

Rødevand L, Rahman Z, Hindley GFL, Smeland OB, Frei O, Tekin TF, Kutrolli G, Bahrami S, Hoseth EZ, Shadrin A, Lin A, Djurovic S, Dale AM, Steen NE, Andreassen OA (2023)
Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors
Am J Psychiatry, 180 (11), 815-826
DOI 10.1176/appi.ajp.20220660, PubMed 37752828

Parker N, Cheng W, Hindley GFL, Parekh P, Shadrin AA, Maximov II, Smeland OB, Djurovic S, Dale AM, Westlye LT, Frei O, Andreassen OA (2023)
Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology
Mol Psychiatry, 28 (11), 4924-4932
DOI 10.1038/s41380-023-02264-z, PubMed 37759039

Smeland OB, Kutrolli G, Bahrami S, Fominykh V, Parker N, Hindley GFL, Rødevand L, Jaholkowski P, Tesfaye M, Parekh P, Elvsåshagen T, Grotzinger AD, International Multiple Sclerosis Genetics Consortium (IMSGC), International Headache Genetics Consortium (IHGC), Steen NE, van der Meer D, O'Connell KS, Djurovic S, Dale AM, Shadrin AA, Frei O, Andreassen OA (2023)
The shared genetic risk architecture of neurological and psychiatric disorders: a genome-wide analysis
medRxiv
DOI 10.1101/2023.07.21.23292993, PubMed 37503175

Raffo A, Paulsen J (2023)
The shape of chromatin: insights from computational recognition of geometric patterns in Hi-C data
Brief Bioinform, 24 (5)
DOI 10.1093/bib/bbad302, PubMed 37646128

Hope S, Shadrin AA, Lin A, Bahrami S, Rødevand L, Frei O, Hübenette SJ, Cheng W, Hindley G, Nag H, Ulstein L, Efrim-Budisteanu M, O'Connell K, Dale AM, Djurovic S, Nærland T, Andreassen OA (2023)
Bidirectional genetic overlap between autism spectrum disorder and cognitive traits
Transl Psychiatry, 13 (1), 295
DOI 10.1038/s41398-023-02563-7, PubMed 37709755

Leich E, Brodtkorb M, Schmidt T, Altenbuchinger M, Lingjærde OC, Lockmer S, Holte H, Nedeva T, Grieb T, Sander B, Sundström C, Spang R, Kimby E, Rosenwald A (2023)
Gene expression and copy number profiling of follicular lymphoma biopsies from patients treated with first-line rituximab without chemotherapy
Leuk Lymphoma, 64 (12), 1927-1937
DOI 10.1080/10428194.2023.2240462, PubMed 37683053

Steen NE, Rahman Z, Szabo A, Hindley GFL, Parker N, Cheng W, Lin A, O'Connell KS, Sheikh MA, Shadrin A, Bahrami S, Karthikeyan S, Hoseth EZ, Dale AM, Aukrust P, Smeland OB, Ueland T, Frei O, Djurovic S, Andreassen OA (2023)
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities
Schizophr Bull, 49 (5), 1345-1354
DOI 10.1093/schbul/sbad082, PubMed 37319439

Namløs HM, Khelik K, Nakken S, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2023)
Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
Mol Oncol, 17 (11), 2432-2450
DOI 10.1002/1878-0261.13514, PubMed 37622176

Boen R, Kaufmann T, van der Meer D, Frei O, Agartz I, Ames D, Andersson M, Armstrong NJ, Artiges E, Atkins JR, Bauer J, Benedetti F, Boomsma DI, Brodaty H, Brosch K, Buckner RL, Cairns MJ, Calhoun V, Caspers S, Cichon S, Corvin AP, Crespo-Facorro B, Dannlowski U, David FS, de Geus EJC et al. (2023)
Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers
Biol Psychiatry, 95 (2), 147-160
DOI 10.1016/j.biopsych.2023.08.018, PubMed 37661008

Isaksen KT, Galleberg R, Mastroianni MA, Rinde M, Rusten LS, Barzenje D, Ramslien F, Fluge O, Slaaen M, Meyer P, Liestol K, Smeland EB, Lingjarde OC, Holte H, Brodtkorb M (2023)
The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
Haematologica, 108 (9), 2454-2466
DOI 10.3324/haematol.2022.282289, PubMed 36861406

Hindley G, Drange OK, Lin A, Kutrolli G, Shadrin AA, Parker N, O'Connell KS, Rødevand L, Cheng W, Bahrami S, Karadag N, Holen B, Jaholkowski P, Woldeyohannes MT, Djurovic S, Dale AM, Frei O, Ueland T, Smeland OB, Andreassen OA (2023)
Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders
Psychoneuroendocrinology, 157, 106368
DOI 10.1016/j.psyneuen.2023.106368, PubMed 37659117

Akdeniz BC, Mattingsdal M, Dominguez-Valentin M, Frei O, Shadrin A, Puustusmaa M, Saar R, Sõber S, Møller P, Andreassen OA, Padrik P, Hovig E (2023)
A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
Cancers (Basel), 15 (16)
DOI 10.3390/cancers15164124, PubMed 37627152

Nakken S, Gundersen S, Bernal FLM, Polychronopoulos D, Hovig E, Wesche J (2023)
Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR
Int J Cancer, 153 (10), 1819-1828
DOI 10.1002/ijc.34666, PubMed 37551617

Tesfaye M, Jaholkowski P, Hindley GFL, Shadrin AA, Rahman Z, Bahrami S, Lin A, Holen B, Parker N, Cheng W, Rødevand L, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA (2023)
Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis
Genome Med, 15 (1), 60
DOI 10.1186/s13073-023-01212-4, PubMed 37528461

Bogaard M, Skotheim RI, Maltau AV, Kidd SG, Lothe RA, Axcrona K, Axcrona U (2023)
'High proliferative cribriform prostate cancer' defines a patient subgroup with an inferior prognosis
Histopathology, 83 (6), 853-869
DOI 10.1111/his.15012, PubMed 37501635

Lizana L, Nahali N, Schwartz YB (2023)
Polycomb proteins translate histone methylation to chromatin folding
J Biol Chem, 299 (9), 105080
DOI 10.1016/j.jbc.2023.105080, PubMed 37499944

Erikssen G, Liestøl K, Aboulhosn J, Wik G, Holmstrøm H, Døhlen G, Gjesdal O, Birkeland S, Hoel TN, Saatvedt KJ, Seem E, Thaulow E, Estensen ME, Lindberg HL (2023)
Preoperative versus postoperative survival in patients with univentricular heart: a nationwide, retrospective study of patients born in 1990-2015
BMJ Open, 13 (7), e069531
DOI 10.1136/bmjopen-2022-069531, PubMed 37491095

Kalyanasundaram S, Lefol Y, Gundersen S, Rognes T, Alsøe L, Nilsen HL, Hovig E, Sandve GK, Domanska D (2023)
hGSuite HyperBrowser: A web-based toolkit for hierarchical metadata-informed analysis of genomic tracks
PLoS One, 18 (7), e0286330
DOI 10.1371/journal.pone.0286330, PubMed 37467208

Dube Mandishora RS, Rounge TB, Fitzpatrick M, Christiansen IK, Ambur OH, Lagström S, Stray-Pedersen B, Tommasino M, Palefsky J, Chirenje ZM (2023)
Correction: Self-collected and clinician-collected anal swabs show modest agreement for HPV genotyping
PLoS One, 18 (7), e0288418
DOI 10.1371/journal.pone.0288418, PubMed 37418482

Oddsson A, Sulem P, Sveinbjornsson G, Arnadottir GA, Steinthorsdottir V, Halldorsson GH, Atlason BA, Oskarsson GR, Helgason H, Nielsen HS, Westergaard D, Karjalainen JM, Katrinardottir H, Fridriksdottir R, Jensson BO, Tragante V, Ferkingstad E, Jonsson H, Gudjonsson SA, Beyter D, Moore KHS, Thordardottir HB, Kristmundsdottir S, Stefansson OA, Rantapää-Dahlqvist S et al. (2023)
Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3923
DOI 10.1038/s41467-023-39492-4, PubMed 37400429

Jaholkowski P, Shadrin AA, Jangmo A, Frei E, Tesfaye M, Hindley GFL, Haram M, Rahman Z, Athanasiu L, Bakken NR, Holen B, Fominykh V, Kutrolli G, Parekh P, Parker N, Rødevand L, Birkenæs V, Djurovic S, Frei O, O'Connell KS, Smeland OB, Tesli M, Andreassen OA (2023)
Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders
JAMA Psychiatry, 80 (7), 738-742
DOI 10.1001/jamapsychiatry.2023.1137, PubMed 37163253

Mufford MS, van der Meer D, Kaufmann T, Frei O, Ramesar R, Thompson PM, Jahanshad N, Morey RA, Andreassen OA, Stein DJ, Dalvie S (2023)
The Genetic Architecture of Amygdala Nuclei
Biol Psychiatry, 95 (1), 72-84
DOI 10.1016/j.biopsych.2023.06.022, PubMed 37391117

Hindley G, Shadrin AA, van der Meer D, Parker N, Cheng W, O'Connell KS, Bahrami S, Lin A, Karadag N, Holen B, Bjella T, Deary IJ, Davies G, Hill WD, Bressler J, Seshadri S, Fan CC, Ueland T, Djurovic S, Smeland OB, Frei O, Dale AM, Andreassen OA (2023)
Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy
Nat Hum Behav, 7 (9), 1584-1600
DOI 10.1038/s41562-023-01630-9, PubMed 37365406

Umu SU, Paynter VM, Trondsen H, Buschmann T, Rounge TB, Peterson KJ, Fromm B (2023)
Accurate microRNA annotation of animal genomes using trained covariance models of curated microRNA complements in MirMachine
Cell Genom, 3 (8), 100348
DOI 10.1016/j.xgen.2023.100348, PubMed 37601971

Heimark S, Mehlum MH, Mancia G, Søraas CL, Liestøl K, Wachtell K, Larstorp AC, Rostrup M, Mariampillai JE, Kjeldsen SE, Julius S, Weber MA (2023)
Middle-Aged and Older Patients With Left Ventricular Hypertrophy: Higher Mortality With Drug Treated Systolic Blood Pressure Below 130 mm Hg
Hypertension, 80 (8), 1739-1748
DOI 10.1161/HYPERTENSIONAHA.123.21454, PubMed 37350267

Shakibfar S, Nyberg F, Li H, Zhao J, Nordeng HME, Sandve GKF, Pavlovic M, Hajiebrahimi M, Andersen M, Sessa M (2023)
Artificial intelligence-driven prediction of COVID-19-related hospitalization and death: a systematic review
Front Public Health, 11, 1183725
DOI 10.3389/fpubh.2023.1183725, PubMed 37408750

Oddsson A, Sulem P, Sveinbjornsson G, Arnadottir GA, Steinthorsdottir V, Halldorsson GH, Atlason BA, Oskarsson GR, Helgason H, Nielsen HS, Westergaard D, Karjalainen JM, Katrinardottir H, Fridriksdottir R, Jensson BO, Tragante V, Ferkingstad E, Jonsson H, Gudjonsson SA, Beyter D, Moore KHS, Thordardottir HB, Kristmundsdottir S, Stefansson OA, Rantapää-Dahlqvist S et al. (2023)
Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3453
DOI 10.1038/s41467-023-38951-2, PubMed 37301908

Fominykh V, Shadrin AA, Jaholkowski PP, Bahrami S, Athanasiu L, Wightman DP, Uffelmann E, Posthuma D, Selbæk G, Dale AM, Djurovic S, Frei O, Andreassen OA (2023)
Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system
Neurobiol Dis, 183, 106174
DOI 10.1016/j.nbd.2023.106174, PubMed 37286172

Cheng W, Parker N, Karadag N, Koch E, Hindley G, Icick R, Shadrin A, O'Connell KS, Bjella T, Bahrami S, Rahman Z, Tesfaye M, Jaholkowski P, Rødevand L, Holen B, Lagerberg TV, Steen NE, Djurovic S, Dale AM, Frei O, Smeland OB, Andreassen OA (2023)
The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study
Lancet Psychiatry, 10 (6), 441-451
DOI 10.1016/S2215-0366(23)00143-8, PubMed 37208114

Kvaerner AS, Andersen AR, Henriksen HB, Knudsen MD, Johansen AMW, Hjartåker A, Bøhn SK, Paur I, Wiedswang G, Smeland S, Rounge TB, Blomhoff R, Berstad P (2023)
Associations of the 2018 World Cancer Research Fund/American Institute of Cancer Research (WCRF/AICR) cancer prevention recommendations with stages of colorectal carcinogenesis
Cancer Med, 12 (13), 14806-14819
DOI 10.1002/cam4.6119, PubMed 37212529

Olstad EW, Nordeng HME, Sandve GK, Lyle R, Gervin K (2023)
Effects of prenatal exposure to (es)citalopram and maternal depression during pregnancy on DNA methylation and child neurodevelopment
Transl Psychiatry, 13 (1), 149
DOI 10.1038/s41398-023-02441-2, PubMed 37147306

Reas ET, Shadrin A, Frei O, Motazedi E, McEvoy L, Bahrami S, van der Meer D, Makowski C, Loughnan R, Wang X, Broce I, Banks SJ, Fominykh V, Cheng W, Holland D, Smeland OB, Seibert T, Selbaek G, Brewer JB, Fan CC, Andreassen OA, Dale AM, Alzheimer's Disease Neuroimaging Initiative (2023)
Improved multimodal prediction of progression from MCI to Alzheimer's disease combining genetics with quantitative brain MRI and cognitive measures
Alzheimers Dement, 19 (11), 5151-5158
DOI 10.1002/alz.13112, PubMed 37132098

Wæhler HA, Labba NA, Paulsen RE, Sandve GK, Eskeland R (2023)
ANDA: An open-source tool for automated image analysis of neuronal differentiation
bioRxiv
DOI 10.1101/2023.04.27.538564, PubMed 37162841

Bucher-Johannessen C, Birkeland EE, Vinberg E, Bemanian V, Hoff G, Berstad P, Rounge TB (2023)
Long-term follow-up of colorectal cancer screening attendees identifies differences in Phascolarctobacterium spp. using 16S rRNA and metagenome sequencing
Front Oncol, 13, 1183039
DOI 10.3389/fonc.2023.1183039, PubMed 37182146

O'Connell KS, Koch E, Lenk HÇ, Akkouh IA, Hindley G, Jaholkowski P, Smith RL, Holen B, Shadrin AA, Frei O, Smeland OB, Steen NE, Dale AM, Molden E, Djurovic S, Andreassen OA (2023)
Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia
Psychiatry Res, 325, 115217
DOI 10.1016/j.psychres.2023.115217, PubMed 37146461

Al Hajj GS, Pensar J, Sandve GK (2023)
DagSim: Combining DAG-based model structure with unconstrained data types and relations for flexible, transparent, and modularized data simulation
PLoS One, 18 (4), e0284443
DOI 10.1371/journal.pone.0284443, PubMed 37058511

Smith DM, Loughnan R, Friedman NP, Parekh P, Frei O, Thompson WK, Andreassen OA, Neale M, Jernigan TL, Dale AM (2023)
Heritability Estimation of Cognitive Phenotypes in the ABCD Study^® Using Mixed Models
Behav Genet, 53 (3), 169-188
DOI 10.1007/s10519-023-10141-2, PubMed 37024669

Dominguez-Valentin M, Haupt S, Seppälä TT, Sampson JR, Sunde L, Bernstein I, Jenkins MA, Engel C, Aretz S, Nielsen M, Capella G, Balaguer F, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Della Valle A et al. (2023)
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
EClinicalMedicine, 58, 101909
DOI 10.1016/j.eclinm.2023.101909, PubMed 37181409

Makowski C, Wang H, Srinivasan A, Qi A, Qiu Y, van der Meer D, Frei O, Zou J, Visscher PM, Yang J, Chen CH (2023)
Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness
Proc Natl Acad Sci U S A, 120 (11), e2214834120
DOI 10.1073/pnas.2214834120, PubMed 36893272

Hesselberg Løvestad A, Stosic MS, Costanzi JM, Christiansen IK, Aamot HV, Ambur OH, Rounge TB (2023)
TaME-seq2: tagmentation-assisted multiplex PCR enrichment sequencing for viral genomic profiling
Virol J, 20 (1), 44
DOI 10.1186/s12985-023-02002-5, PubMed 36890572

Boen R, Kaufmann T, Frei O, van der Meer D, Djurovic S, Andreassen OA, Selmer KK, Alnæs D, Sønderby IE (2023)
No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank
Transl Psychiatry, 13 (1), 61
DOI 10.1038/s41398-023-02358-w, PubMed 36807331

Meier Strømme J, Johannessen B, Skotheim RI (2023)
Deviating Alternative Splicing as a Molecular Subtype of Microsatellite Stable Colorectal Cancer
JCO Clin Cancer Inform, 7, e2200159
DOI 10.1200/CCI.22.00159, PubMed 36821799

Andreassen OA, Hindley GFL, Frei O, Smeland OB (2023)
New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications
World Psychiatry, 22 (1), 4-24
DOI 10.1002/wps.21034, PubMed 36640404

Cavalieri S, Vener C, LeBlanc M, Lopez-Perez L, Fico G, Resteghini C, Monzani D, Marton G, Pravettoni G, Moreira-Soares M, Filippidou DE, Almeida A, Bilbao A, Mehanna H, Singer S, Thomas S, Lacerenza L, Manfuso A, Copelli C, Mercalli F, Frigessi A, Martinelli E, Licitra L, BD4QoL Consortium (2023)
A multicenter randomized trial for quality of life evaluation by non-invasive intelligent tools during post-curative treatment follow-up for head and neck cancer: Clinical study protocol
Front Oncol, 13, 1048593
DOI 10.3389/fonc.2023.1048593, PubMed 36798825

Senthakumaran T, Moen AEF, Tannæs TM, Endres A, Brackmann SA, Rounge TB, Bemanian V, Tunsjø HS (2023)
Microbial dynamics with CRC progression: a study of the mucosal microbiota at multiple sites in cancers, adenomatous polyps, and healthy controls
Eur J Clin Microbiol Infect Dis, 42 (3), 305-322
DOI 10.1007/s10096-023-04551-7, PubMed 36703031

Chlubnová M, Christophersen AO, Sandve GKF, Lundin KEA, Jahnsen J, Dahal-Koirala S, Sollid LM (2023)
Identification of gluten T cell epitopes driving celiac disease
Sci Adv, 9 (4), eade5800
DOI 10.1126/sciadv.ade5800, PubMed 36696493

Knutsen TM, Skretteberg PT, Vanberg P, Kamal Z, Halvorsen S, Liestøl K, Steen T, Platou E (2023)
Transvenous lead extractions in a single high-volume center over a 24-year period: High success rate and low complication rate
Heart Rhythm O2, 4 (4), 232-240
DOI 10.1016/j.hroo.2023.01.003, PubMed 37124554

Rodríguez-Varela R, Moore KHS, Ebenesersdóttir SS, Kilinc GM, Kjellström A, Papmehl-Dufay L, Alfsdotter C, Berglund B, Alrawi L, Kashuba N, Sobrado V, Lagerholm VK, Gilbert E, Cavalleri GL, Hovig E, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Munters AR, Bernhardsson C, Skar B, Christophersen A, Turner-Walker G et al. (2023)
The genetic history of Scandinavia from the Roman Iron Age to the present
Cell, 186 (1), 32-46.e19
DOI 10.1016/j.cell.2022.11.024, PubMed 36608656

Strøm TB, Asprusten E, Laerdahl JK, Øygard I, Hussain MM, Bogsrud MP, Leren TP (2023)
Missense mutation Q384K in the APOB gene affecting the large lipid transfer module of apoB reduces the secretion of apoB-100 in the liver without reducing the secretion of apoB-48 in the intestine
J Clin Lipidol, 17 (6), 800-807
DOI 10.1016/j.jacl.2023.08.009, PubMed 37718180

Abu-Halima M, Keller A, Becker LS, Fischer U, Engel A, Ludwig N, Kern F, Rounge TB, Langseth H, Meese E, Keller V (2023)
Dynamic and static circulating cancer microRNA biomarkers - a validation study
RNA Biol, 20 (1), 1-9
DOI 10.1080/15476286.2022.2154470, PubMed 36511578

Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
screenwerk: a modular tool for the design and analysis of drug combination screens
Bioinformatics, 39 (1)
DOI 10.1093/bioinformatics/btac840, PubMed 36573326

Publications 2022

Høye E, Dagenborg VJ, Torgunrud A, Lund-Andersen C, Fretland ÅA, Lorenz S, Edwin B, Hovig E, Fromm B, Inderberg EM, Greiff V, Ree AH, Flatmark K (2022)
T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
Gigascience, 12
DOI 10.1093/gigascience/giad032, PubMed 37161965

Kanduri C, Scheffer L, Pavlović M, Rand KD, Chernigovskaya M, Pirvandy O, Yaari G, Greiff V, Sandve GK (2022)
simAIRR: simulation of adaptive immune repertoires with realistic receptor sequence sharing for benchmarking of immune state prediction methods
Gigascience, 12
DOI 10.1093/gigascience/giad074, PubMed 37848619

Robert PA, Akbar R, Frank R, Pavlović M, Widrich M, Snapkov I, Slabodkin A, Chernigovskaya M, Scheffer L, Smorodina E, Rawat P, Mehta BB, Vu MH, Mathisen IF, Prósz A, Abram K, Olar A, Miho E, Haug DTT, Lund-Johansen F, Hochreiter S, Haff IH, Klambauer G, Sandve GK, Greiff V (2022)
Unconstrained generation of synthetic antibody-antigen structures to guide machine learning methodology for antibody specificity prediction
Nat Comput Sci, 2 (12), 845-865
DOI 10.1038/s43588-022-00372-4, PubMed 38177393

Axcrona K, Aas K, Axcrona U, Skotheim RI (2022)
Re: Spatially Resolved Clonal Copy Number Alterations in Benign and Malignant Tissue
Eur Urol, 83 (2), 183
DOI 10.1016/j.eururo.2022.11.013, PubMed 36464529

Rossini R, Kumar V, Mathelier A, Rognes T, Paulsen J (2022)
MoDLE: high-performance stochastic modeling of DNA loop extrusion interactions
Genome Biol, 23 (1), 247
DOI 10.1186/s13059-022-02815-7, PubMed 36451166

Giliberto M, Santana LM, Holien T, Misund K, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Coward E, Waage A, Taskén K, Skånland SS (2022)
Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
Front Oncol, 12, 1040730
DOI 10.3389/fonc.2022.1040730, PubMed 36523963

Castro-Mondragon JA, Aure MR, Lingjærde OC, Langerød A, Martens JWM, Børresen-Dale AL, Kristensen VN, Mathelier A (2022)
Cis-regulatory mutations associate with transcriptional and post-transcriptional deregulation of gene regulatory programs in cancers
Nucleic Acids Res, 50 (21), 12131-12148
DOI 10.1093/nar/gkac1143, PubMed 36477895

van der Meer D, Gurholt TP, Sønderby IE, Shadrin AA, Hindley G, Rahman Z, de Lange AG, Frei O, Leinhard OD, Linge J, Simon R, Beck D, Westlye LT, Halvorsen S, Dale AM, Karlsen TH, Kaufmann T, Andreassen OA (2022)
The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
Commun Biol, 5 (1), 1271
DOI 10.1038/s42003-022-04237-4, PubMed 36402844

Zavaleta E, Solis N, Palacios MI, Zevallos-Escobar LE, Corales EV, Bazo-Alvarez JC, Dominguez-Barrera C, Campos A, Wernhoff P, Ekstrøm PO, Møller P, Visnovska T, Hovig E, Balazar-Palacios J, Alvarez-Valenzuela K, Nakken S, Dominguez-Valentin M (2022)
Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
Cancers (Basel), 14 (22)
DOI 10.3390/cancers14225603, PubMed 36428697

Sandve GK, Greiff V (2022)
Access to ground truth at unconstrained size makes simulated data as indispensable as experimental data for bioinformatics methods development and benchmarking
Bioinformatics, 38 (21), 4994-4996
DOI 10.1093/bioinformatics/btac612, PubMed 36073940

Alver TN, Heintz KM, Hovig E, Bøe SL (2022)
Cooperative induction of receptor tyrosine kinases contributes to adaptive MAPK drug resistance in melanoma through the PI3K pathway
Cancer Rep (Hoboken), 6 (2), e1736
DOI 10.1002/cnr2.1736, PubMed 36251678

Feldmann D, Bope CD, Patricios J, Chimusa ER, Collins M, September AV (2022)
A whole genome sequencing approach to anterior cruciate ligament rupture-a twin study in two unrelated families
PLoS One, 17 (10), e0274354
DOI 10.1371/journal.pone.0274354, PubMed 36201451

Grytten I, Dagestad Rand K, Sandve GK (2022)
KAGE: fast alignment-free graph-based genotyping of SNPs and short indels
Genome Biol, 23 (1), 209
DOI 10.1186/s13059-022-02771-2, PubMed 36195962

Gopalakrishnan S, Ebenesersdóttir SS, Lundstrøm IKC, Turner-Walker G, Moore KHS, Luisi P, Margaryan A, Martin MD, Ellegaard MR, Magnússon ÓÞ, Sigurðsson Á, Snorradóttir S, Magnúsdóttir DN, Laffoon JE, van Dorp L, Liu X, Moltke I, Ávila-Arcos MC, Schraiber JG, Rasmussen S, Juan D, Gelabert P, de-Dios T, Fotakis AK, Iraeta-Orbegozo M et al. (2022)
The population genomic legacy of the second plague pandemic
Curr Biol, 32 (21), 4743-4751.e6
DOI 10.1016/j.cub.2022.09.023, PubMed 36182700

Møller P, Seppälä T, Dowty JG, Haupt S, Dominguez-Valentin M, Sunde L, Bernstein I, Engel C, Aretz S, Nielsen M, Capella G, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Valle AD, Heinimann K et al. (2022)
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
Hered Cancer Clin Pract, 20 (1), 36
DOI 10.1186/s13053-022-00241-1, PubMed 36182917

Flobak Å, Skånland SS, Hovig E, Taskén K, Russnes HG (2022)
Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
Trends Pharmacol Sci, 43 (11), 973-985
DOI 10.1016/j.tips.2022.08.009, PubMed 36163057

Chetty M, Roomaney I, Oosterwyk C, Manyisa N, Bope CD, Agenbag G, Wonkam A (2022)
Craniofacial, dental, and molecular features of Pyle disease in a South African child
BDJ Open, 8 (1), 28
DOI 10.1038/s41405-022-00120-w, PubMed 36138002

Loughnan RJ, Shadrin AA, Frei O, van der Meer D, Zhao W, Palmer CE, Thompson WK, Makowski C, Jernigan TL, Andreassen OA, Fan CC, Dale AM (2022)
Generalization of cortical MOSTest genome-wide associations within and across samples
Neuroimage, 263, 119632
DOI 10.1016/j.neuroimage.2022.119632, PubMed 36115590

Løvestad AH, Repesa A, Costanzi JM, Lagström S, Christiansen IK, Rounge TB, Ambur OH (2022)
Differences in integration frequencies and APOBEC3 profiles of five high-risk HPV types adheres to phylogeny
Tumour Virus Res, 14, 200247
DOI 10.1016/j.tvr.2022.200247, PubMed 36100161

Ellingsen EB, Bounova G, Kerzeli I, Anzar I, Simnica D, Aamdal E, Guren T, Clancy T, Mezheyeuski A, Inderberg EM, Mangsbo SM, Binder M, Hovig E, Gaudernack G (2022)
Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
J Transl Med, 20 (1), 419
DOI 10.1186/s12967-022-03624-z, PubMed 36089578

Kværner AS, Birkeland E, Vinberg E, Hoff G, Hjartåker A, Rounge TB, Berstad P (2022)
Associations of red and processed meat intake with screen-detected colorectal lesions
Br J Nutr, 129 (12), 1-11 (in press)
DOI 10.1017/S0007114522002860, PubMed 36069337

Hindley G, Frei O, Shadrin AA, Cheng W, O'Connell KS, Icick R, Parker N, Bahrami S, Karadag N, Roelfs D, Holen B, Lin A, Fan CC, Djurovic S, Dale AM, Smeland OB, Andreassen OA (2022)
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation
Am J Psychiatry, 179 (11), 833-843
DOI 10.1176/appi.ajp.21101051, PubMed 36069018

Grasso C, Popovic M, Isaevska E, Lazzarato F, Fiano V, Zugna D, Pluta J, Weathers B, D'Andrea K, Almstrup K, Anson-Cartwright L, Bishop DT, Chanock SJ, Chen C, Cortessis VK, Dalgaard MD, Daneshmand S, Ferlin A, Foresta C, Frone MN, Gamulin M, Gietema JA, Greene MH, Grotmol T, Hamilton RJ et al. (2022)
Association Study between Polymorphisms in DNA Methylation-Related Genes and Testicular Germ Cell Tumor Risk
Cancer Epidemiol Biomarkers Prev, 31 (9), 1769-1779
DOI 10.1158/1055-9965.EPI-22-0123, PubMed 35700037

Rognes T, Scheffer L, Greiff V, Sandve GK (2022)
CompAIRR: ultra-fast comparison of adaptive immune receptor repertoires by exact and approximate sequence matching
Bioinformatics, 38 (17), 4230-4232
DOI 10.1093/bioinformatics/btac505, PubMed 35852318

Przybyła W, Gjersvoll Paulsen KM, Mishra CK, Nygård S, Engebretsen S, Ruud E, Trøen G, Beiske K, Baumbusch LO (2022)
Whole exome sequencing of high-risk neuroblastoma identifies novel non-synonymous variants
PLoS One, 17 (8), e0273280
DOI 10.1371/journal.pone.0273280, PubMed 36037157

Lobert VH, Skardal ML, Malerød L, Simensen JE, Algra HA, Andersen AN, Fleischer T, Enserink HA, Liestøl K, Heath JK, Rusten TE, Stenmark HA (2022)
PHLPP1 regulates CFTR activity and lumen expansion through AMPK
Development, 149 (20)
DOI 10.1242/dev.200955, PubMed 35997536

Weber CR, Rubio T, Wang L, Zhang W, Robert PA, Akbar R, Snapkov I, Wu J, Kuijjer ML, Tarazona S, Conesa A, Sandve GK, Liu X, Reddy ST, Greiff V (2022)
Reference-based comparison of adaptive immune receptor repertoires
Cell Rep Methods, 2 (8), 100269
DOI 10.1016/j.crmeth.2022.100269, PubMed 36046619

Venizelos A, Engebrethsen C, Deng W, Geisler J, Geisler S, Iversen GT, Aas T, Aase HS, Seyedzadeh M, Steinskog ES, Myklebost O, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Lønning PE, Knappskog S, Eikesdal HP (2022)
Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy
Genome Med, 14 (1), 86
DOI 10.1186/s13073-022-01090-2, PubMed 35948919

Icick R, Shadrin A, Holen B, Karadag N, Lin A, Hindley G, O'Connell K, Frei O, Bahrami S, Høegh MC, Cheng W, Fan CC, Djurovic S, Dale AM, Lagerberg TV, Smeland OB, Andreassen OA (2022)
Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings
Neuropsychopharmacology, 47 (11), 1883-1891
DOI 10.1038/s41386-022-01401-6, PubMed 35953530

Kleppe A, Skrede OJ, De Raedt S, Hveem TS, Askautrud HA, Jacobsen JE, Church DN, Nesbakken A, Shepherd NA, Novelli M, Kerr R, Liestøl K, Kerr DJ, Danielsen HE (2022)
A clinical decision support system optimising adjuvant chemotherapy for colorectal cancers by integrating deep learning and pathological staging markers: a development and validation study
Lancet Oncol, 23 (9), 1221-1232
DOI 10.1016/S1470-2045(22)00391-6, PubMed 35964620

Carm KT, Johannessen B, Bogaard M, Bakken AC, Maltau AV, Hoff AM, Axcrona U, Axcrona K, Lothe RA, Skotheim RI (2022)
Somatic mutations reveal complex metastatic seeding from multifocal primary prostate cancer
Int J Cancer, 152 (5), 945-951
DOI 10.1002/ijc.34226, PubMed 35880692

Balaban G, Halliday BP, Hammersley D, Rinaldi CA, Prasad SK, Bishop MJ, Lamata P (2022)
Left ventricular shape predicts arrhythmic risk in fibrotic dilated cardiomyopathy
Europace, 24 (7), 1137-1147
DOI 10.1093/europace/euab306, PubMed 34907426

Hindley G, O'Connell KS, Rahman Z, Frei O, Bahrami S, Shadrin A, Høegh MC, Cheng W, Karadag N, Lin A, Rødevand L, Fan CC, Djurovic S, Lagerberg TV, Dale AM, Smeland OB, Andreassen OA (2022)
The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis
Am J Med Genet B Neuropsychiatr Genet, 189 (6), 207-218
DOI 10.1002/ajmg.b.32907, PubMed 35841185

Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 317
DOI 10.1186/s12967-022-03518-0, PubMed 35841045

Olstad EW, Nordeng HME, Sandve GK, Lyle R, Gervin K (2022)
Low reliability of DNA methylation across Illumina Infinium platforms in cord blood: implications for replication studies and meta-analyses of prenatal exposures
Clin Epigenetics, 14 (1), 80
DOI 10.1186/s13148-022-01299-3, PubMed 35765087

Chimusa ER, Alosaimi S, Bope CD (2022)
Dissecting Generalizability and Actionability of Disease-Associated Genes From 20 Worldwide Ethnolinguistic Cultural Groups
Front Genet, 13, 835713
DOI 10.3389/fgene.2022.835713, PubMed 35812734

Kidd SG, Bogaard M, Carm KT, Bakken AC, Maltau AMV, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI (2022)
In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis
Mol Oncol, 16 (15), 2810-2822
DOI 10.1002/1878-0261.13225, PubMed 35574900

Bahrami S, Nordengen K, Shadrin AA, Frei O, van der Meer D, Dale AM, Westlye LT, Andreassen OA, Kaufmann T (2022)
Distributed genetic architecture across the hippocampal formation implies common neuropathology across brain disorders
Nat Commun, 13 (1), 3436
DOI 10.1038/s41467-022-31086-w, PubMed 35705537

Burton J, Wojewodzic MW, Rounge TB, Haugen TB (2022)
A Role of the TEX101 Interactome in the Common Aetiology Behind Male Subfertility and Testicular Germ Cell Tumor
Front Oncol, 12, 892043
DOI 10.3389/fonc.2022.892043, PubMed 35774118

Silwal-Pandit L, Stålberg SM, Johansson HJ, Mermelekas G, Lothe IMB, Skrede ML, Dalsgaard AM, Nebdal DJH, Helland Å, Lingjærde OC, Labori KJ, Skålhegg BS, Lehtiö J, Kure EH (2022)
Proteome Analysis of Pancreatic Tumors Implicates Extracellular Matrix in Patient Outcome
Cancer Res Commun, 2 (6), 434-446
DOI 10.1158/2767-9764.CRC-21-0100, PubMed 36923555

Misund K, Hofste Op Bruinink D, Coward E, Hoogenboezem RM, Rustad EH, Sanders MA, Rye M, Sponaas AM, van der Holt B, Zweegman S, Hovig E, Meza-Zepeda LA, Sundan A, Myklebost O, Sonneveld P, Waage A (2022)
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
Leukemia, 36 (7), 1887-1897
DOI 10.1038/s41375-022-01597-y, PubMed 35643867

Kanduri C, Pavlović M, Scheffer L, Motwani K, Chernigovskaya M, Greiff V, Sandve GK (2022)
Profiling the baseline performance and limits of machine learning models for adaptive immune receptor repertoire classification
Gigascience, 11
DOI 10.1093/gigascience/giac046, PubMed 35639633

Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 225
DOI 10.1186/s12967-022-03432-5, PubMed 35568909

Torgersen K, Rahman Z, Bahrami S, Hindley GFL, Parker N, Frei O, Shadrin A, O'Connell KS, Tesli M, Smeland OB, Munkhaugen J, Djurovic S, Dammen T, Andreassen OA (2022)
Shared genetic loci between depression and cardiometabolic traits
PLoS Genet, 18 (5), e1010161
DOI 10.1371/journal.pgen.1010161, PubMed 35560157

Fan CC, Loughnan R, Makowski C, Pecheva D, Chen CH, Hagler DJ, Thompson WK, Parker N, van der Meer D, Frei O, Andreassen OA, Dale AM (2022)
Multivariate genome-wide association study on tissue-sensitive diffusion metrics highlights pathways that shape the human brain
Nat Commun, 13 (1), 2423
DOI 10.1038/s41467-022-30110-3, PubMed 35505052

Ellingsen EB, Aamdal E, Guren T, Lilleby W, Brunsvig PF, Mangsbo SM, Aamdal S, Hovig E, Mensali N, Gaudernack G, Inderberg EM (2022)
Durable and dynamic hTERT immune responses following vaccination with the long-peptide cancer vaccine UV1: long-term follow-up of three phase I clinical trials
J Immunother Cancer, 10 (5)
DOI 10.1136/jitc-2021-004345, PubMed 35613827

Taskén K, Russnes HEG, Aas E, Bjørge L, Blix ES, CONNECT Public–Private Partnership Consortium, Enerly E, Fagereng GL, Flobak Å, Gilje B, Gjertsen BT, Guren TK, Heix J, Hovig E, Hovland R, InPreD-Norway and National Molecular Tumor Board Consortium, IMPRESS-Norway Consortium, Lønning PE, Meza-Zepeda LA, Mæhle PM, Nilsen HL, Thoresen SØ, Widerberg K, Smeland S, Helland Å (2022)
A national precision cancer medicine implementation initiative for Norway
Nat Med, 28 (5), 885-887
DOI 10.1038/s41591-022-01777-4, PubMed 35513529

Khadse A, Haakensen VD, Silwal-Pandit L, Hamfjord J, Micke P, Botling J, Brustugun OT, Lingjærde OC, Helland Å, Kure EH (2022)
Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma
Front Oncol, 12, 873532
DOI 10.3389/fonc.2022.873532, PubMed 35574381

Saevarsdottir S, Stefansdottir L, Sulem P, Thorleifsson G, Ferkingstad E, Rutsdottir G, Glintborg B, Westerlind H, Grondal G, Loft IC, Sorensen SB, Lie BA, Brink M, Ärlestig L, Arnthorsson AO, Baecklund E, Banasik K, Bank S, Bjorkman LI, Ellingsen T, Erikstrup C, Frei O, Gjertsson I, Gudbjartsson DF, Gudjonsson SA et al. (2022)
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Ann Rheum Dis, 81 (8), 1085-1095
DOI 10.1136/annrheumdis-2021-221754, PubMed 35470158

Wolowczyk C, Neckmann U, Aure MR, Hall M, Johannessen B, Zhao S, Skotheim RI, Andersen SB, Zwiggelaar R, Steigedal TS, Lingjærde OC, Sahlberg KK, Almaas E, Bjørkøy G (2022)
NRF2 drives an oxidative stress response predictive of breast cancer
Free Radic Biol Med, 184, 170-184
DOI 10.1016/j.freeradbiomed.2022.03.029, PubMed 35381325

Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G et al. (2022)
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Nature, 604 (7906), 502-508
DOI 10.1038/s41586-022-04434-5, PubMed 35396580

Bahrami S, Hindley G, Winsvold BS, O'Connell KS, Frei O, Shadrin A, Cheng W, Bettella F, Rødevand L, Odegaard KJ, Fan CC, Pirinen MJ, Hautakangas HM, HUNT All-In Headache, Dale AM, Djurovic S, Smeland OB, Andreassen OA (2022)
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools
Brain, 145 (1), 142-153
DOI 10.1093/brain/awab267, PubMed 34273149

Yadav A, Gupta S, Istvan P, Ronen Z (2022)
Effects of Perchlorate and Other Groundwater Inorganic Co-Contaminants on Aerobic RDX Degradation
Microorganisms, 10 (3)
DOI 10.3390/microorganisms10030663, PubMed 35336238

Dahal-Koirala S, Balaban G, Neumann RS, Scheffer L, Lundin KEA, Greiff V, Sollid LM, Qiao SW, Sandve GK (2022)
TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences
Brief Bioinform, 23 (2)
DOI 10.1093/bib/bbab566, PubMed 35062022

Jorgensen M, Halkjelsvik T, Liestol K (2022)
When should we (not) use the mean magnitude of relative error (MMRE) as an error measure in software development effort estimation?
Inf. Softw. Technol., 143, 106784
DOI 10.1016/j.infsof.2021.106784

Strømme JM, Johannessen B, Kidd SG, Bogaard M, Carm KT, Zhang X, Sveen A, Mathelier A, Lothe RA, Axcrona U, Axcrona K, Skotheim RI (2022)
Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity
Cancer Gene Ther, 29 (8-9), 1276-1284
DOI 10.1038/s41417-022-00444-7, PubMed 35194199

Fontugne J, Cai PY, Alnajar H, Bhinder B, Park K, Ye H, Beg S, Sailer V, Siddiqui J, Blattner-Johnson M, Croyle JA, Noorzad Z, Calagua C, MacDonald TY, Axcrona U, Bogaard M, Axcrona K, Scherr DS, Sanda MG, Johannessen B, Chinnaiyan AM, Elemento O, Skotheim RI, Rubin MA, Barbieri CE et al. (2022)
Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci
JCI Insight, 7 (4)
DOI 10.1172/jci.insight.155309, PubMed 35050902

Umu SU, Langseth H, Zuber V, Helland Å, Lyle R, Rounge TB (2022)
Serum RNAs can predict lung cancer up to 10 years prior to diagnosis
Elife, 11
DOI 10.7554/eLife.71035, PubMed 35147498

van der Meer D, Shadrin AA, O'Connell K, Bettella F, Djurovic S, Wolfers T, Alnæs D, Agartz I, Smeland OB, Melle I, Sánchez JM, Linden DEJ, Dale AM, Westlye LT, Andreassen OA, Frei O, Kaufmann T (2022)
Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology
Biol Psychiatry, 92 (4), 291-298
DOI 10.1016/j.biopsych.2021.12.007, PubMed 35164939

Blandino A, Scherer D, Rounge TB, Umu SU, Boekstegers F, Barahona Ponce C, Marcelain K, Gárate-Calderón V, Waldenberger M, Morales E, Rojas A, Munoz C, Retamales J, de Toro G, Barajas O, Rivera MT, Cortés A, Loader D, Saavedra J, Gutiérrez L, Ortega A, Bertrán ME, Gabler F, Campos M, Alvarado J et al. (2022)
Identification of Circulating lncRNAs Associated with Gallbladder Cancer Risk by Tissue-Based Preselection, Cis-eQTL Validation, and Analysis of Association with Genotype-Based Expression
Cancers (Basel), 14 (3)
DOI 10.3390/cancers14030634, PubMed 35158906

Høye E, Fromm B, Böttger PHM, Domanska D, Torgunrud A, Lund-Andersen C, Abrahamsen TW, Fretland ÅA, Dagenborg VJ, Lorenz S, Edwin B, Hovig E, Flatmark K (2022)
A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer
NAR Cancer, 4 (1), zcab051
DOI 10.1093/narcan/zcab051, PubMed 35047825

Skotheim RI, Axcrona U, Axcrona K (2022)
Re: Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
Eur Urol, 81 (4), 431
DOI 10.1016/j.eururo.2021.12.031, PubMed 35031159

Fromm B, Høye E, Domanska D, Zhong X, Aparicio-Puerta E, Ovchinnikov V, Umu SU, Chabot PJ, Kang W, Aslanzadeh M, Tarbier M, Mármol-Sánchez E, Urgese G, Johansen M, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2022)
MirGeneDB 2.1: toward a complete sampling of all major animal phyla
Nucleic Acids Res, 50 (D1), D204-D210
DOI 10.1093/nar/gkab1101, PubMed 34850127

Paulsen J, Collas P (2022)
Modeling the 3D Genome Using Hi-C and Nuclear Lamin-Genome Contacts
Methods Mol Biol, 2301, 337-352
DOI 10.1007/978-1-0716-1390-0_18, PubMed 34415545

Motazedi E, Cheng W, Thomassen JQ, Frei O, Rongve A, Athanasiu L, Bahrami S, Shadrin A, Ulstein I, Stordal E, Brækhus A, Saltvedt I, Sando SB, O'Connell KS, Hindley G, van der Meer D, Bergh S, Nordestgaard BG, Tybjærg-Hansen A, Bråthen G, Pihlstrøm L, Djurovic S, Frikke-Schmidt R, Fladby T, Aarsland D et al. (2022)
Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations
J Alzheimers Dis, 88 (4), 1533-1544
DOI 10.3233/JAD-220174, PubMed 35848024

Akbar R, Robert PA, Weber CR, Widrich M, Frank R, Pavlović M, Scheffer L, Chernigovskaya M, Snapkov I, Slabodkin A, Mehta BB, Miho E, Lund-Johansen F, Andersen JT, Hochreiter S, Hobæk Haff I, Klambauer G, Sandve GK, Greiff V (2022)
In silico proof of principle of machine learning-based antibody design at unconstrained scale
MAbs, 14 (1), 2031482
DOI 10.1080/19420862.2022.2031482, PubMed 35377271

Publications 2021

Mahé F, Czech L, Stamatakis A, Quince C, de Vargas C, Dunthorn M, Rognes T (2021)
Swarm v3: towards tera-scale amplicon clustering
Bioinformatics, 38 (1), 267-269
DOI 10.1093/bioinformatics/btab493, PubMed 34244702

van der Meer D, Kaufmann T, Shadrin AA, Makowski C, Frei O, Roelfs D, Monereo-Sánchez J, Linden DEJ, Rokicki J, Alnæs D, de Leeuw C, Thompson WK, Loughnan R, Fan CC, Westlye LT, Andreassen OA, Dale AM (2021)
The genetic architecture of human cortical folding
Sci Adv, 7 (51), eabj9446
DOI 10.1126/sciadv.abj9446, PubMed 34910505

Lien TG, Ohnstad HO, Lingjærde OC, Vallon-Christersson J, Aaserud M, Sveli MAT, Borg Å, Osbreac OBO, Garred Ø, Borgen E, Naume B, Russnes H, Sørlie T (2021)
Sample Preparation Approach Influences PAM50 Risk of Recurrence Score in Early Breast Cancer
Cancers (Basel), 13 (23)
DOI 10.3390/cancers13236118, PubMed 34885228

Jorgensen M, Bergersen GR, Liestol K (2021)
Relations Between Effort Estimates, Skill Indicators, and Measured Programming Skill
IEEE Trans. Softw. Eng., 47 (12), 2892-2906
DOI 10.1109/TSE.2020.2973638

Simões RF, Pino R, Moreira-Soares M, Kovarova J, Neuzil J, Travasso R, Oliveira PJ, Cunha-Oliveira T, Pereira FB (2021)
Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine
FASEB J, 35 (12), e22024
DOI 10.1096/fj.202100899R, PubMed 34751984

Isaksen KT, Mastroianni MA, Rinde M, Rusten LS, Barzenje DA, Ramslien LF, Slaaen M, Jerm MB, Smeland EB, Rostoft S, Liestøl K, Brodtkorb M, Holte H (2021)
A simplified frailty score predicts survival and can aid treatment-intensity decisions in older patients with DLBCL
Blood Adv, 5 (22), 4771-4782
DOI 10.1182/bloodadvances.2021004777, PubMed 34543384

Slabodkin A, Chernigovskaya M, Mikocziova I, Akbar R, Scheffer L, Pavlović M, Bashour H, Snapkov I, Mehta BB, Weber CR, Gutierrez-Marcos J, Sollid LM, Haff IH, Sandve GK, Robert PA, Greiff V (2021)
Individualized VDJ recombination predisposes the available Ig sequence space
Genome Res, 31 (12), 2209-2224
DOI 10.1101/gr.275373.121, PubMed 34815307

Oncu AE, Ozdemir HU, Orhan HI, Akdeniz BCC, Toprakci A, Aslihak MA, Yilmaz HB, Pusane AE, Tugcu T, Dinc F (2021)
Analytical Investigation of Long-Time Diffusion Dynamics in a Synaptic Channel With Glial Cells
IEEE Commun. Lett., 25 (11), 3444-3448
DOI 10.1109/LCOMM.2021.3105613

Pavlović M, Scheffer L, Motwani K, Kanduri C, Kompova R, Vazov N, Waagan K, Bernal FLM, Costa AA, Corrie B, Akbar R, Al Hajj GS, Balaban G, Brusko TM, Chernigovskaya M, Christley S, Cowell LG, Frank R, Grytten I, Gundersen S, Haff IH, Hovig E, Hsieh PH, Klambauer G, Kuijjer ML et al. (2021)
The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires
Nat Mach Intell, 3 (11), 936-944
DOI 10.1038/s42256-021-00413-z, PubMed 37396030

Falk RS, Mariampillai JE, Prestgaard EE, Heir T, Bodegård J, Robsahm TE, Grundvold I, Skretteberg PT, Engeseth K, Bjornholt JV, Stavem K, Liestøl K, Sandvik L, Thaulow E, Erikssen G, Kjeldsen SE, Gjesdal K, Erikssen JE (2021)
The Oslo Ischaemia Study: cohort profile
BMJ Open, 11 (10), e049111
DOI 10.1136/bmjopen-2021-049111, PubMed 34645662

Bjaanæs MM, Nilsen G, Halvorsen AR, Russnes HG, Solberg S, Jørgensen L, Brustugun OT, Lingjærde OC, Helland Å (2021)
Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors
BMC Cancer, 21 (1), 1089
DOI 10.1186/s12885-021-08811-7, PubMed 34625038

Yao Y, Wyrozżemski Ł, Lundin KEA, Sandve GK, Qiao SW (2021)
Differential expression profile of gluten-specific T cells identified by single-cell RNA-seq
PLoS One, 16 (10), e0258029
DOI 10.1371/journal.pone.0258029, PubMed 34618841

Pihlstrøm L, Fan CC, Frei O, Tan M, Karunamuni RA, Blauwendraat C, Bandres-Ciga S, Gan-Or Z, Grosset DG, International Parkinson's Disease Genomics Consortium (IPDGC), Dale AM, Seibert TM, Andreassen OA (2021)
Genetic Stratification of Age-Dependent Parkinson's Disease Risk by Polygenic Hazard Score
Mov Disord, 37 (1), 62-69
DOI 10.1002/mds.28808, PubMed 34612543

Wiström ED, O'Connell KS, Karadag N, Bahrami S, Hindley GFL, Lin A, Cheng W, Steen NE, Shadrin A, Frei O, Djurovic S, Dale AM, Andreassen OA, Smeland OB (2021)
Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci
Addiction, 117 (3), 600-610
DOI 10.1111/add.15680, PubMed 34472679

Mariampillai JE, Prestgaard EE, Kjeldsen SE, Liestøl K, Grundvold I, Bodegård J, Gjesdal K, Erikssen JE, Skretteberg PT (2021)
Novel insights into stroke risk beyond resting and maximal bicycle exercise systolic blood pressure
J Hypertens, 39 (10), 2022-2029
DOI 10.1097/HJH.0000000000002894, PubMed 34102659

Hindley G, Bahrami S, Steen NE, O'Connell KS, Frei O, Shadrin A, Bettella F, Rødevand L, Fan CC, Dale AM, Djurovic S, Smeland OB, Andreassen OA (2021)
Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
Transl Psychiatry, 11 (1), 466
DOI 10.1038/s41398-021-01576-4, PubMed 34497263

Sveen A, Johannessen B, Eilertsen IA, Røsok BI, Gulla M, Eide PW, Bruun J, Kryeziu K, Meza-Zepeda LA, Myklebost O, Bjørnbeth BA, Skotheim RI, Nesbakken A, Lothe RA (2021)
The expressed mutational landscape of microsatellite stable colorectal cancers
Genome Med, 13 (1), 142
DOI 10.1186/s13073-021-00955-2, PubMed 34470667

Kværner AS, Birkeland E, Bucher-Johannessen C, Vinberg E, Nordby JI, Kangas H, Bemanian V, Ellonen P, Botteri E, Natvig E, Rognes T, Hovig E, Lyle R, Ambur OH, de Vos WM, Bultman S, Hjartåker A, Landberg R, Song M, Blix HS, Ursin G, Randel KR, de Lange T, Hoff G, Holme Ø et al. (2021)
The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
BMC Cancer, 21 (1), 930
DOI 10.1186/s12885-021-08640-8, PubMed 34407780

Nakken S, Saveliev V, Hofmann O, Møller P, Myklebost O, Hovig E (2021)
Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
Int J Cancer, 149 (11), 1955-1960
DOI 10.1002/ijc.33749, PubMed 34310709

Rødevand L, Bahrami S, Frei O, Chu Y, Shadrin A, O'Connell KS, Smeland OB, Elvsåshagen T, Hindley GFL, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA (2021)
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
Transl Psychiatry, 11 (1), 407
DOI 10.1038/s41398-021-01527-z, PubMed 34301917

Pluta J, Pyle LC, Nead KT, Wilf R, Li M, Mitra N, Weathers B, D'Andrea K, Almstrup K, Anson-Cartwright L, Benitez J, Brown CD, Chanock S, Chen C, Cortessis VK, Ferlin A, Foresta C, Gamulin M, Gietema JA, Grasso C, Greene MH, Grotmol T, Hamilton RJ, Haugen TB, Hauser R et al. (2021)
Identification of 22 susceptibility loci associated with testicular germ cell tumors
Nat Commun, 12 (1), 4487
DOI 10.1038/s41467-021-24334-y, PubMed 34301922

Bergland OU, Halvorsen LV, Søraas CL, Hjørnholm U, Kjær VN, Rognstad S, Brobak KM, Aune A, Olsen E, Fauchald YM, Heimark S, Thorstensen CW, Liestøl K, Solbu MD, Gerdts E, Mo R, Rostrup M, Kjeldsen SE, Høieggen A, Opdal MS, Larstorp ACK, Fadl Elmula FEM (2021)
Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations
Hypertension, 78 (3), 617-628
DOI 10.1161/HYPERTENSIONAHA.121.17514, PubMed 34275336

Rye IH, Huse K, Josefsson SE, Kildal W, Danielsen HE, Schlichting E, Garred Ø, Riis ML, Osbreac, Lingjaerde OC, Myklebust JH, Russnes HG (2021)
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression
Mol Oncol, 16 (1), 88-103
DOI 10.1002/1878-0261.13047, PubMed 34165864

Ellingsen EB, Mangsbo SM, Hovig E, Gaudernack G (2021)
Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential
Front Immunol, 12, 682492
DOI 10.3389/fimmu.2021.682492, PubMed 34290704

Monereo-Sánchez J, Schram MT, Frei O, O'Connell K, Shadrin AA, Smeland OB, Westlye LT, Andreassen OA, Kaufmann T, Linden DEJ, van der Meer D (2021)
Genetic Overlap Between Alzheimer's Disease and Depression Mapped Onto the Brain
Front Neurosci, 15, 653130
DOI 10.3389/fnins.2021.653130, PubMed 34290577

Liyakat Ali TM, Brunet A, Collas P, Paulsen J (2021)
TAD cliques predict key features of chromatin organization
BMC Genomics, 22 (1), 499
DOI 10.1186/s12864-021-07815-8, PubMed 34217222

Dominguez-Valentin M, Plazzer JP, Sampson JR, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Macrae F, Winship IM, Thomas H, Evans DG, Burn J, Greenblatt M, de Vos Tot Nederveen Cappel WH, Sijmons RH, Nielsen M, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Lindblom A, Valle AD et al. (2021)
No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study
J Clin Med, 10 (13)
DOI 10.3390/jcm10132856, PubMed 34203177

Lagström S, Løvestad AH, Umu SU, Ambur OH, Nygård M, Rounge TB, Christiansen IK (2021)
HPV16 and HPV18 type-specific APOBEC3 and integration profiles in different diagnostic categories of cervical samples
Tumour Virus Res, 12, 200221
DOI 10.1016/j.tvr.2021.200221, PubMed 34175494

Holland D, Frei O, Desikan R, Fan CC, Shadrin AA, Smeland OB, Andreassen OA, Dale AM (2021)
Erratum to: The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity
Genetics, 218 (2)
DOI 10.1093/genetics/iyab064, PubMed 34167151

Torgersen K, Bahrami S, Frei O, Shadrin A, Connell KSO, Smeland OB, Munkhaugen J, Djurovic S, Dammen T, Andreassen OA (2021)
Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors
Transl Psychiatry, 11 (1), 368
DOI 10.1038/s41398-021-01466-9, PubMed 34226488

Brägelmann J, Barahona Ponce C, Marcelain K, Roessler S, Goeppert B, Gallegos I, Colombo A, Sanhueza V, Morales E, Rivera MT, de Toro G, Ortega A, Müller B, Gabler F, Scherer D, Waldenberger M, Reischl E, Boekstegers F, Garate-Calderon V, Umu SU, Rounge TB, Popanda O, Lorenzo Bermejo J (2021)
Epigenome-Wide Analysis of Methylation Changes in the Sequence of Gallstone Disease, Dysplasia, and Gallbladder Cancer
Hepatology, 73 (6), 2293-2310
DOI 10.1002/hep.31585, PubMed 33020926

Egan M, Akdeniz BC, Tang BQ (2021)
Equilibrium Signaling in Spatially Inhomogeneous Diffusion and External Forces
IEEE T. Mol. Biol. Multi-Scale Commun., 7 (2), 106-110
DOI 10.1109/TMBMC.2021.3054908

Kidd SG, Carm KT, Bogaard M, Olsen LG, Bakken AC, Løvf M, Lothe RA, Axcrona K, Axcrona U, Skotheim RI (2021)
High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity
Neoplasia, 23 (6), 634-641
DOI 10.1016/j.neo.2021.05.012, PubMed 34107378

Ramberg H, Richardsen E, de Souza GA, Rakaee M, Stensland ME, Braadland PR, Nygård S, Ögren O, Guldvik IJ, Berge V, Svindland A, Taskén KA, Andersen S (2021)
Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
Carcinogenesis, 42 (5), 685-693
DOI 10.1093/carcin/bgab015, PubMed 33609362

Hamfjord J, Guren TK, Glimelius B, Sorbye H, Pfeiffer P, Dajani O, Lingjaerde OC, Tveit KM, Pallisgaard N, Spindler KG, Kure EH (2021)
Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer
Int J Cancer, 149 (6), 1385-1397
DOI 10.1002/ijc.33672, PubMed 33961700

Eriksson AM, Leikfoss IS, Abrahamsen G, Sundvold V, Isom MM, Keshari PK, Rognes T, Landsverk OJB, Bos SD, Harbo HF, Spurkland A, Berge T (2021)
Exploring the role of the multiple sclerosis susceptibility gene CLEC16A in T cells
Scand J Immunol, 94 (1), e13050
DOI 10.1111/sji.13050, PubMed 34643957

Elvsåshagen T, Shadrin A, Frei O, van der Meer D, Bahrami S, Kumar VJ, Smeland O, Westlye LT, Andreassen OA, Kaufmann T (2021)
The genetic architecture of the human thalamus and its overlap with ten common brain disorders
Nat Commun, 12 (1), 2909
DOI 10.1038/s41467-021-23175-z, PubMed 34006833

Gurholt TP, Kaufmann T, Frei O, Alnæs D, Haukvik UK, van der Meer D, Moberget T, O'Connell KS, Leinhard OD, Linge J, Simon R, Smeland OB, Sønderby IE, Winterton A, Steen NE, Westlye LT, Andreassen OA (2021)
Population-based body-brain mapping links brain morphology with anthropometrics and body composition
Transl Psychiatry, 11 (1), 295
DOI 10.1038/s41398-021-01414-7, PubMed 34006848

Mattingsdal M, Ebenesersdóttir SS, Moore KHS, Andreassen OA, Hansen TF, Werge T, Kockum I, Olsson T, Alfredsson L, Helgason A, Stefánsson K, Hovig E (2021)
The genetic structure of Norway
Eur J Hum Genet, 29 (11), 1710-1718
DOI 10.1038/s41431-021-00899-6, PubMed 34002043

Wojewodzic MW, Leithaug M, Lauritzen M, Lyle R, Haglund S, Rubin CJ, Ewels PA, Grotmol T, Rounge TB (2021)
Ultralow amounts of DNA from long-term archived serum samples produce high-quality methylomes
Clin Epigenetics, 13 (1), 107
DOI 10.1186/s13148-021-01097-3, PubMed 33980276

Aamdal E, Inderberg EM, Ellingsen EB, Rasch W, Brunsvig PF, Aamdal S, Heintz KM, Vodák D, Nakken S, Hovig E, Nyakas M, Guren TK, Gaudernack G (2021)
Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial
Front Immunol, 12, 663865
DOI 10.3389/fimmu.2021.663865, PubMed 34046035

Dube Mandishora RS, Rounge TB, Fitzpatrick M, Christiansen IK, Ambur OH, Lagström S, Stray-Pedersen B, Tommasino M, Palefsky J, Chirenje ZM (2021)
Self-collected and clinician-collected anal swabs show modest agreement for HPV genotyping
PLoS One, 16 (4), e0250426
DOI 10.1371/journal.pone.0250426, PubMed 33901223

Lemma RB, Ledsaak M, Fuglerud BM, Sandve GK, Eskeland R, Gabrielsen OS (2021)
Chromatin occupancy and target genes of the haematopoietic master transcription factor MYB
Sci Rep, 11 (1), 9008
DOI 10.1038/s41598-021-88516-w, PubMed 33903675

Nakken S, Lilleby W, Switlyk MD, Knudsen KE, Lilleby O, Zhao S, Kaveh F, Ekstrøm PO, Urbanucci A, Hovig E (2021)
The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology
J Pers Med, 11 (5)
DOI 10.3390/jpm11050330, PubMed 33922147

Dahal-Koirala S, Risnes LF, Neumann RS, Christophersen A, Lundin KEA, Sandve GK, Qiao SW, Sollid LM (2021)
Comprehensive Analysis of CDR3 Sequences in Gluten-Specific T-Cell Receptors Reveals a Dominant R-Motif and Several New Minor Motifs
Front Immunol, 12, 639672
DOI 10.3389/fimmu.2021.639672, PubMed 33927715

Gundersen S, Boddu S, Capella-Gutierrez S, Drabløs F, Fernández JM, Kompova R, Taylor K, Titov D, Zerbino D, Hovig E (2021)
Recommendations for the FAIRification of genomic track metadata
F1000Res, 10
DOI 10.12688/f1000research.28449.1, PubMed 34249331

Maximov II, van der Meer D, de Lange AG, Kaufmann T, Shadrin A, Frei O, Wolfers T, Westlye LT (2021)
Fast qualitY conTrol meThod foR derIved diffUsion Metrics (YTTRIUM) in big data analysis: U.K. Biobank 18,608 example
Hum Brain Mapp, 42 (10), 3141-3155
DOI 10.1002/hbm.25424, PubMed 33788350

Akdeniz BC, Egan M (2021)
Molecular Communication for Equilibrium State Estimation in Biochemical Processes on a Lab-on-a-Chip
IEEE Trans Nanobioscience, 20 (2), 193-201
DOI 10.1109/TNB.2021.3062473, PubMed 33635792

Snipen L, Angell IL, Rognes T, Rudi K (2021)
Reduced metagenome sequencing for strain-resolution taxonomic profiles
Microbiome, 9 (1), 79
DOI 10.1186/s40168-021-01019-8, PubMed 33781324

Seppälä TT, Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2021)
Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
Eur J Cancer, 148, 124-133
DOI 10.1016/j.ejca.2021.02.022, PubMed 33743481

Akbar R, Robert PA, Pavlović M, Jeliazkov JR, Snapkov I, Slabodkin A, Weber CR, Scheffer L, Miho E, Haff IH, Haug DTT, Lund-Johansen F, Safonova Y, Sandve GK, Greiff V (2021)
A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding
Cell Rep, 34 (11), 108856
DOI 10.1016/j.celrep.2021.108856, PubMed 33730590

Balaban G, Grytten I, Rand KD, Scheffer L, Sandve GK (2021)
Ten simple rules for quick and dirty scientific programming
PLoS Comput Biol, 17 (3), e1008549
DOI 10.1371/journal.pcbi.1008549, PubMed 33705383

Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Sci Transl Med, 13 (582)
DOI 10.1126/scitranslmed.abb0036, PubMed 33627483

Akdeniz BC, Egan M, Tang BQ (2021)
Equilibrium Signaling: Molecular Communication Robust to Geometry Uncertainties
IEEE Trans. Commun., 69 (2), 752-765
DOI 10.1109/TCOMM.2020.3034662

Kleppe A, Skrede OJ, De Raedt S, Liestøl K, Kerr DJ, Danielsen HE (2021)
Designing deep learning studies in cancer diagnostics
Nat Rev Cancer, 21 (3), 199-211
DOI 10.1038/s41568-020-00327-9, PubMed 33514930

Haugen MH, Lingjærde OC, Hedenfalk I, Garred Ø, Borgen E, Loman N, Hatschek T, Børresen-Dale AL, Naume B, Mills GB, Mælandsmo GM, Engebraaten O (2021)
Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers
JCO Precis Oncol, 5
DOI 10.1200/PO.20.00086, PubMed 34036235

Kanduri C, Sandve GK, Hovig E, De S, Layer RM (2021)
Editorial: Genomic Colocalization and Enrichment Analyses
Front Genet, 11, 617876
DOI 10.3389/fgene.2020.617876, PubMed 33574832

Liestøl K, Kleppe A, Skrede OJ, De Raedt S, Kerr DJ, Danielsen HE (2021)
Deep learning and cancer biomarkers: recognising lead-time bias - Authors' reply
Lancet, 397 (10270), 194-195
DOI 10.1016/S0140-6736(21)00035-0, PubMed 33453777

Safavi S, Larouche A, Zahn A, Patenaude AM, Domanska D, Dionne K, Rognes T, Dingler F, Kang SK, Liu Y, Johnson N, Hébert J, Verdun RE, Rada CA, Vega F, Nilsen H, Noia JMD (2021)
Erratum: The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID
NAR Cancer, 3 (1), zcaa045
DOI 10.1093/narcan/zcaa045, PubMed 34316697

Rødevand L, Bahrami S, Frei O, Lin A, Gani O, Shadrin A, Smeland OB, Connell KSO, Elvsåshagen T, Winterton A, Quintana DS, Hindley GFL, Werner MCF, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA (2021)
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
Transl Psychiatry, 11 (1), 3
DOI 10.1038/s41398-020-01142-4, PubMed 33414458

Nikolaidis K, Kristiansen S, Plagemann T, Goebel V, Liestol K, Kankanhalli M, Traaen GM, Overland B, Akre H, Aakeroy L, Steinshamn S (2021)
Learning Realistic Patterns from Visually Unrealistic Stimuli: Generalization and Data Anonymization
J. Artif. Intell. Res., 72, 1163-1214

Publications 2020

Ask EH, Tschan-Plessl A, Gjerdingen TJ, Sætersmoen ML, Hoel HJ, Wiiger MT, Olweus J, Wahlin BE, Lingjærde OC, Horowitz A, Cashen AF, Watkins M, Fehniger TA, Holte H, Kolstad A, Malmberg KJ (2020)
A Systemic Protein Deviation Score Linked to PD-1⁺ CD8⁺ T Cell Expansion That Predicts Overall Survival in Diffuse Large B Cell Lymphoma
Med, 2 (2), 180-195.e5
DOI 10.1016/j.medj.2020.10.006, PubMed 35590201

Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Nakken S, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2020)
Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
Genet Med, 23 (4), 705-712
DOI 10.1038/s41436-020-01029-1, PubMed 33257847

Di Stefano M, Paulsen J, Jost D, Marti-Renom MA (2020)
4D nucleome modeling
Curr Opin Genet Dev, 67, 25-32
DOI 10.1016/j.gde.2020.10.004, PubMed 33253996

Zhao S, Agafonov O, Azab A, Stokowy T, Hovig E (2020)
Accuracy and efficiency of germline variant calling pipelines for human genome data
Sci Rep, 10 (1), 20222
DOI 10.1038/s41598-020-77218-4, PubMed 33214604

Yao Y, Zia A, Neumann RS, Pavlovic M, Balaban G, Lundin KEA, Sandve GK, Qiao SW (2020)
T cell receptor repertoire as a potential diagnostic marker for celiac disease
Clin Immunol, 222, 108621
DOI 10.1016/j.clim.2020.108621, PubMed 33197618

Balaban G, Halliday BP, Porter B, Bai W, Nygåard S, Owen R, Hatipoglu S, Ferreira ND, Izgi C, Tayal U, Corden B, Ware J, Pennell DJ, Rueckert D, Plank G, Rinaldi CA, Prasad SK, Bishop MJ (2020)
Late-Gadolinium Enhancement Interface Area and Electrophysiological Simulations Predict Arrhythmic Events in Patients With Nonischemic Dilated Cardiomyopathy
JACC Clin Electrophysiol, 7 (2), 238-249
DOI 10.1016/j.jacep.2020.08.036, PubMed 33602406

Burton J, Umu SU, Langseth H, Grotmol T, Grimsrud TK, Haugen TB, Rounge TB (2020)
Serum RNA Profiling in the 10-Years Period Prior to Diagnosis of Testicular Germ Cell Tumor
Front Oncol, 10, 574977
DOI 10.3389/fonc.2020.574977, PubMed 33251139

Salgado D, Armean IM, Baudis M, Beltran S, Capella-Gutierrez S, Carvalho-Silva D, Dominguez Del Angel V, Dopazo J, Furlong LI, Gao B, Garcia L, Gerloff D, Gut I, Gyenesei A, Habermann N, Hancock JM, Hanauer M, Hovig E, Johansson LF, Keane T, Korbel J, Lauer KB, Laurie S, Leskošek B, Lloyd D et al. (2020)
The ELIXIR Human Copy Number Variations Community: building bioinformatics infrastructure for research
F1000Res, 9
DOI 10.12688/f1000research.24887.1, PubMed 34367618

Farooq A, Grønmyr S, Ali O, Rognes T, Scheffler K, Bjørås M, Wang J (2020)
HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data
Comput Struct Biotechnol J, 18, 2877-2889
DOI 10.1016/j.csbj.2020.09.038, PubMed 33163148