What is needed is not a single map, but rather an atlas of how these processes unfold across a variety of cell types, disease states and cellular processes. The bioinformatics environment in Oslo are making contributions in several directions - improving the fundamental understanding of how the genome is spatially organized and how transcription factors bind to DNA, developing statistical methodology for analyzing relations between omics data and determining spatial enrichment.
Principal Investigators: Geir Kjetil Sandve, Jonas Paulsen