Recent publications - Department of Pharmaceutical Chemistry

• Mazetto de Carvalho, Mariana; Eltvik, Andrea Angelov; Ellefsen, Christiane Færestrand; Hiorth, Marianne & Samuelsen, Anne Berit C. (2024). Coating of liposomes with β-glucans from the king oyster mushroom (Pleurotus eryngii). Colloids and Surfaces A: Physicochemical and Engineering Aspects. ISSN 0927-7757. doi: 10.1016/j.colsurfa.2024.134783.
• Dalaker, Vivian Moe; Furuhaugen, Håvard; Brekke, Mette; Bjørnaas, Mari Asphjell; Krpo, Maja & Øiestad, Elisabeth Leere [Show all 7 contributors for this article] (2024). Drugs in blood and urine samples from victims of suspected exposure to drink spiking: a prospective observational study from Oslo, Norway. PLOS ONE. ISSN 1932-6203. 19.
• Bakke, Eirin; Nilsen, Mariann; Strand, Dag Helge; Øiestad, Elisabeth Leere & Høiseth, Gudrun (2024). Enantiomer-specific analysis of amphetamine in urine, oral fluid and blood. Journal of Analytical Toxicology. ISSN 0146-4760. 48(5), p. 254–262. doi: 10.1093/jat/bkae038.
• Bjune, Katrine; skovholt halvorsen, pia; Wangensteen, Helle; Leren, Trond Paul; Bogsrud, Martin Prøven & Strøm, Thea Bismo (2024). Flavonoids regulate LDLR through different mechanisms tied to their specific structures. Journal of Lipid Research. ISSN 0022-2275. 65(5). doi: 10.1016/j.jlr.2024.100539.
• Reubsaet, Leon & Halvorsen, Trine Grønhaug (2024). Advancements in clinical approaches, analytical methods, and smart sampling for LC–MS-based protein determination from dried matrix spots. Journal of Separation Science. ISSN 1615-9306. 47(9-10). doi: 10.1002/jssc.202400061.
• Zhang, Chao-Wen; Zou, Yuanfeng; Zou, Yun; JiZe, Xiao-Ping; Li, Cen-Yu & Fu, Yu-Ping [Show all 18 contributors for this article] (2024). Ultrasonic-assisted extraction of polysaccharide from Paeoniae Radix alba: Extraction optimization, structural characterization and antioxidant mechanism in vitro. International Journal of Biological Macromolecules. ISSN 0141-8130. 268. doi: 10.1016/j.ijbiomac.2024.131816.
• Johnsen, Hennie Marie; Hossaini Nasr, Seyedmehdi; De Luna, Ricardo; Filtvedt, Werner Olav; Sailor, Michael J. & Klaveness, Jo [Show all 7 contributors for this article] (2024). Stable “snow lantern-like” aggregates of silicon nanoparticles suitable as a drug delivery platform. Nanoscale. ISSN 2040-3364. doi: 10.1039/d3nr05655d.
• Zeraatkar Moghaddam, Ali; Tabani, Hadi; Bameri, Amirehsan; Arabi, Elahe; Alexovič, Michal & Pedersen-Bjergaard, Stig (2024). Agarose-based gel electromembrane extraction using silica nanoparticles coated with polymeric deep eutectic solvent as a membrane additive. Journal of Molecular Liquids. ISSN 0167-7322. 401. doi: 10.1016/j.molliq.2024.124615.
• Fabris, André Luis; Pedersen-Bjergaard, Stig; Øiestad, Elisabeth Leere; Rossi, Giordano Novak; Hallak, Jaime E.Cecílio & dos Santos, Rafael Guimarães [Show all 8 contributors for this article] (2024). Solvent-free parallel artificial liquid membrane extraction for drugs of abuse in plasma samples using LC-MS/MS. Analytica Chimica Acta. ISSN 0003-2670. 1301. doi: 10.1016/j.aca.2024.342387.
• Foss, Stian; Sakya, Siri Aastedatter; Aguinagalde, Leire; Lustig, Marta; Shaughnessy, Jutamas & Cruz, Ana Rita [Show all 25 contributors for this article] (2024). Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria. Nature Communications. ISSN 2041-1723. 15(1). doi: 10.1038/s41467-024-46321-9.
• Fabris, André L.; Hansen, Frederik Andre; Yonamine, Mauricio; Pedersen-Bjergaard, Stig & Øiestad, Elisabeth Leere (2024). An efficient and green method for the analysis of synthetic cathinones in whole blood using 96-well electromembrane extraction and LC-MS/MS. Sustainable Chemistry and Pharmacy. ISSN 2352-5541. 38, p. 1–12. doi: 10.1016/j.scp.2024.101494.
• Hoel, Håvard; de Boer, Hugo; Kool, Anneleen & Wangensteen, Helle (2024). Analysis of bitter compounds in traditional preparations of Gentiana purpurea L. Fitoterapia. ISSN 0367-326X. 175. doi: 10.1016/j.fitote.2024.105932. Full text in Research Archive
• Rye, Torstein Kige; Dowlatshah, Samira; Hansen, Frederik Andre; Halvorsen, Trine Grønhaug & Pedersen-Bjergaard, Stig (2024). Electromembrane extraction of peptides – Looking retrospectively into published studies. Advances in Sample Preparation. ISSN 2772-5820. 9. doi: 10.1016/j.sampre.2024.100106.
• Wold, Christian Winther; Christopoulos, Panagiotis; Arias, Maykel; Dzovor, Deborah Elikplim; Øynebråten, Inger & Corthay, Alexandre Benoit [Show all 7 contributors for this article] (2024). Fungal polysaccharides from Inonotus obliquus are agonists for Toll-like receptors and induce macrophage anti-cancer activity. Communications Biology. ISSN 2399-3642. 7. doi: 10.1038/s42003-024-05853-y.
• Hrithik, Md Tafim Hossain; Shahmohammadi, Niayesh; Gahyeon, Jin; Lee, Dong-Hee; Singh, Nalin & Vik, Anders [Show all 8 contributors for this article] (2024). Insect immune resolution with EpOME/DiHOME and its dysregulation by their analogs leading to pathogen hypersensitivity. Insect Biochemistry and Molecular Biology. ISSN 0965-1748. 168. doi: 10.1016/j.ibmb.2024.104104.
• Dowlatshah, Samira; Rye, Torstein Kige; Hansen, Frederik Andre; Halvorsen, Trine Grønhaug & Pedersen-Bjergaard, Stig (2024). Parallel electromembrane extraction of peptides with monoterpene and medium-length fatty acid deep eutectic solvents. Analytica Chimica Acta. ISSN 0003-2670. 1297. doi: 10.1016/j.aca.2024.342360.
• Song, Chenchen; Zhou, Chen; Hansen, Frederik Andre; Hay, Anne Oldeide & Pedersen-Bjergaard, Stig (2024). Optimization of generic conditions for electromembrane extraction of basic substances of moderate or low polarity. Journal of Separation Science. ISSN 1615-9306. 47(3). doi: 10.1002/jssc.202300801.
• Nolsøe, Jens Mortansson Jelstrup; Underhaug, Jarl; Sørskår, Åshild Moi; Antonsen, Simen; Malterud, Karl Egil & Gani, Osman [Show all 11 contributors for this article] (2024). Biological Evaluations, NMR Analyses, Molecular Modeling Studies, and Overview of the Synthesis of the Marine Natural Product (−)-Mucosin . Molecules. ISSN 1431-5157. 29(5). doi: 10.3390/molecules29050994. Full text in Research Archive Show summary

  Natural products obtained from marine organisms continue to be a rich source of novel structural architecture and of importance in drug discovery, medicine, and health. However, the success of such endeavors depends on the exact structural elucidation and access to sufficient material, often by stereoselective total synthesis, of the isolated natural product of interest. (−)-Mucosin (1), a fatty acid derivative, previously presumed to contain a rare cis-bicyclo[4.3.0]non-3-ene moiety, has since been shown to be the trans-congener. Analytically, the fused bicyclic ring system in (−)-1 constitutes a particular challenge in order to establish its relative and absolute stereochemistry. Herein, data from biological evaluations, NMR and molecular modeling studies of (−)-1 are presented. An overview of the synthetic strategies enabling the exact structural elucidation of (−)-mucosin (1) is also presented.

• Christensen, Sofie; Gjelstad, Astrid; Björnsdottir, Ingunn & Lauritzen, Fredrik (2024). Medicalization of Sport? A Mixed-Method Study on the Use of Medications in Elite Ice Hockey. Sports. ISSN 2075-4663. 12(1). doi: 10.3390/sports12010019.
• El Menuawy, Ahmed; Brüning, Thomas; Eiriz, Iván; Hähnel, Urs; Marthe, Frank & Möhle, Luisa [Show all 11 contributors for this article] (2024). Apolar Extracts of St. John’s Wort Alleviate the Effects of β-Amyloid Toxicity in Early Alzheimer’s Disease. International Journal of Molecular Sciences. ISSN 1661-6596. 25(2). doi: 10.3390/ijms25021301.
• Felicitas, Mück; Scotti, Francesca; Mauvisseau, Quentin; Thorbek, Birgitte Lisbeth Graae; Wangensteen, Helle & de Boer, Hugo (2024). Three-tiered authentication of herbal traditional Chinese medicine ingredients used in women’s health provides progressive qualitative and quantitative insight. Frontiers in Pharmacology. ISSN 1663-9812. 15. doi: 10.3389/fphar.2024.1353434. Full text in Research Archive
• Moussavi, Nastaran; Mounkoro, Pakuy Pierre; Dembele, Seydou; Ballo, Ngolo; Togola, Adiaratou & Diallo, Drissa [Show all 9 contributors for this article] (2024). Polyherbal combinations used by traditional health practitioners against mental illnesses in Bamako, Mali, West Africa. Plants. ISSN 2223-7747. 13(3). doi: 10.3390/plants13030454. Full text in Research Archive
• Moussavi, Nastaran; van der Ent, Wietske; Diallo, Drissa; Sanogo, Rokia; Malterud, Karl Egil & Esguerra, Camila V. [Show all 7 contributors for this article] (2024). Inhibition of Seizure-Like Paroxysms and Toxicity Effects of Securidaca longepedunculata Extracts and Constituents in Zebrafish Danio rerio. ACS Chemical Neuroscience. ISSN 1948-7193. 15(3), p. 617–628. doi: 10.1021/acschemneuro.3c00642.
• Mrsa, Ago; Nardini, Greta; Halvorsen, Trine Grønhaug; Thiede, Bernd & Reubsaet, Leon (2024). One-step functionalization of paper and simplified antibody immobilization for on-the-spot immunocapture from dried serum in liquid chromatography-tandem mass spectrometry based targeted protein determination. Journal of Mass Spectrometry. ISSN 1076-5174. 59(1). doi: 10.1002/jms.4989. Show summary

  This work aimed to simplify and improve the process of binding monoclonal antibodies (mAbs) covalently to filter paper for use in dried blood spot sampling, enabling instant capture of protein biomarkers for targeted protein determination. Incorporating the necessary immunocapture sample preparation step in the initial sampling stage saves time and reduces the workload. The biomarker human chorionic gonadotropin (hCG) was used as the model analyte. The antibody-based paper samplers were prepared by functionalizing paper discs (6 mm) through a simple reaction using divinyl sulfone (DVS). After DVS activation, the paper discs were incubated with E27 hCG mAbs, followed by 0.05% tween/phosphate buffer saline to block the surface. After sample application and drying, the discs only needed to be washed before tryptic digestion and finally analysed on a nanoliquid chromatography–tandem mass spectrometry system. The finished DVS-mAbs samplers could selectively capture hCG (100 ng/mL) from human serum, with a recovery of 50%. Sample clean-up reduced the number of identified proteins from 132 to 82 before and after wash, respectively, with a 70% reduction in serum albumin signal while still retaining hCG on the sampler during the washing protocol. An evaluation of the samplers revealed excellent linearity (R2 = 0.9995) for hCG in serum with relative standard deviations below 15%. This work has presented the first ever reported paper samplers immobilized with antibodies utilizing DVS chemistry, showing promise in the future of paper-based sampling.

• Butt, Hussain Shakeel; Ulriksen, Emilie Steinbakk; Rise, Frode; Wangensteen, Helle; Duus, Jens Øllgaard & Inngjerdingen, Marit [Show all 7 contributors for this article] (2024). Structural elucidation of novel pro-inflammatory polysaccharides from Daphne mezereum L. Carbohydrate Polymers. ISSN 0144-8617. 324. doi: 10.1016/j.carbpol.2023.121554. Full text in Research Archive
• Johnsen, Hennie Marie; Hiorth, Marianne & Klaveness, Jo (2023). Molecular Hydrogen Therapy—A Review on Clinical Studies and Outcomes. Molecules. ISSN 1431-5157. 28(23). doi: 10.3390/molecules28237785. Full text in Research Archive
• Reinertsen, Amalie Føreid; Libreros, Stephania; Nshimiyimana, Robert; Serhan, Charles Nicholas & Hansen, Trond Vidar (2023). Metabolization of Resolvin E4 by ω-Oxidation in Human Neutrophils: Synthesis and Biological Evaluation of 20-Hydroxy-Resolvin E4 (20-OH-RvE4). ACS Pharmacology & Translational Science. 6(12), p. 1898–1908. doi: 10.1021/acsptsci.3c00201. Full text in Research Archive
• Schüller, Maria; Lucic, Ivana; Øiestad, Åse Marit Leere; Pedersen-Bjergaard, Stig & Øiestad, Elisabeth Leere (2023). High-throughput quantification of emerging “nitazene” benzimidazole opioid analogs by microextraction and UHPLC–MS-MS . Journal of Analytical Toxicology. ISSN 0146-4760. 47(9), p. 787–796. doi: 10.1093/jat/bkad071. Full text in Research Archive
• Mueck, Felicitas; Scotti, Francesca; Mauvisseau, Quentin; Raclariu, Ancuta Cristina; Schrøder-Nielsen, Audun & Wangensteen, Helle [Show all 7 contributors for this article] (2023). Complementary authentication of Chinese herbal products to treat endometriosis using DNA metabarcoding and HPTLC shows a high level of variability. Frontiers in Pharmacology. ISSN 1663-9812. 14. doi: 10.3389/fphar.2023.1305410.
• Sverdvik, Håkon; Gravdahl, Anne; Osmani, Dorentina; Samuelsen, Marius; Sørskår, Åshild Moi & Stenstrøm, Helge Ørjan [Show all 8 contributors for this article] (2023). Bruk av digitale verktøy i kjemiundervisningen. Nordic Journal of STEM Education. ISSN 2535-4574. Full text in Research Archive
• Ervik, Karina; Reinertsen, Amalie Føreid; Koenis, Duco S.; Dalli, Jesmond & Hansen, Trond Vidar (2023). Stereoselective Synthesis, Pro-resolution, and Anti-inflammatory Actions of RvD5n-3 DPA. Journal of natural products. ISSN 0163-3864. 86(11), p. 2546– 2553. doi: 10.1021/acs.jnatprod.3c00769. Full text in Research Archive
• Lien, Vegard Torp; Hauge, Emily; Nuruddin, Syed Mohammad; Klaveness, Jo & Olberg, Dag Erlend (2023). Synthesis and preclinical evaluation of a selective MET kinase positron emission tomography tracer. Journal of labelled compounds & radiopharmaceuticals. ISSN 0362-4803. 66(14), p. 452–460. doi: 10.1002/jlcr.4066.
• Gjelstad, Astrid; Herlofsen, Tine Marie; Bjerke, Anne-Linn; Lauritzen, Fredrik & Björnsdottir, Ingunn (2023). Use of pharmaceuticals amongst athletes tested by Anti-Doping Norway in a five-year period. Frontiers in Sports and Active Living. ISSN 2624-9367. 5. doi: 10.3389/fspor.2023.1260806. Full text in Research Archive
• Haatveit, Åsmund Steinvik & Hansen, Trond Vidar (2023). The biosynthetic pathways of the protectins. Prostaglandins & other lipid mediators. ISSN 1098-8823. 169. doi: 10.1016/j.prostaglandins.2023.106787. Full text in Research Archive
• Fu, Yu-ping; Li, Cen-Yu; Zou, Yuanfeng; Peng, Xi; Paulsen, Berit Smestad & Wangensteen, Helle [Show all 7 contributors for this article] (2023). Bioactive polysaccharides in different plant parts of Aconitum carmichaelii. Journal of the Science of Food and Agriculture. ISSN 0022-5142. 104(2). doi: 10.1002/jsfa.12967. Full text in Research Archive
• Schüller, Maria; Hansen, Frederik Andre & Pedersen-Bjergaard, Stig (2023). Extraction performance of electromembrane extraction and liquid-phase microextraction in prototype equipment. Journal of Chromatography A. ISSN 0021-9673. 1710. doi: 10.1016/j.chroma.2023.464440.
• Martín, Alejandro; Dowlatshah, Samira; Pedersen-Bjergaard, Stig & Ramos-Payán, María (2023). Enhancing liquid phase microextraction enrichment in microchip devices under semi-stagnant conditions. Microchemical Journal. ISSN 0026-265X. 195. doi: 10.1016/j.microc.2023.109383. Full text in Research Archive
• Ellefsen, Christiane Færestrand; Lindstad, Linda; Klau, Leesa Jane; Aachmann, Finn Lillelund; Hiorth, Marianne & Samuelsen, Anne Berit C. (2023). Investigation of the structural and immunomodulatory properties of alkali-soluble β-glucans from Pleurotus eryngii fruiting bodies. Carbohydrate Polymers. ISSN 0144-8617. 322. doi: 10.1016/j.carbpol.2023.121367. Full text in Research Archive
• Karwounopoulos, Johannes; Kaupang, Åsmund; Wieder, Marcus & Boresch, Stefan (2023). Calculations of Absolute Solvation Free Energies with Transformato─Application to the FreeSolv Database Using the CGenFF Force Field. Journal of Chemical Theory and Computation. ISSN 1549-9618. 19(17), p. 5988–5998. doi: 10.1021/acs.jctc.3c00691. Full text in Research Archive
• Dowlatshah, Samira; Hansen, Frederik Andre; Zhou, Chen; Ramos-Payán, María; Halvorsen, Trine Grønhaug & Pedersen-Bjergaard, Stig (2023). Electromembrane extraction of peptides based on hydrogen bond interactions. Analytica Chimica Acta. ISSN 0003-2670. 1275. doi: 10.1016/j.aca.2023.341610. Full text in Research Archive
• Zhou, Chen; Dowlatshah, Samira; Hay, Anne Oldeide; Schüller, Maria; Pedersen-Bjergaard, Stig & Hansen, Frederik Andre (2023). Generic Liquid Membranes for Electromembrane Extraction of Bases with Low or Moderate Hydrophilicity. Analytical Chemistry. ISSN 0003-2700. 95(23), p. 8982–8989. doi: 10.1021/acs.analchem.3c01052. Full text in Research Archive
• Fu, Yu-ping; Malterud, Karl Egil; Hamre, Anne Grethe; Inngjerdingen, Kari Tvete & Wangensteen, Helle (2023). Polysaccharides and Bioactive Phenolics from Aconitum septentrionale Roots. Chemistry and Biodiversity. ISSN 1612-1872. 20(8). doi: 10.1002/cbdv.202300161. Full text in Research Archive
• Schüller, Maria; Hansen, Frederik Andre; Skaalvik, Tonje Gottenberg & Pedersen-Bjergaard, Stig (2023). Conductive vial electromembrane extraction – Principles and practical operation. Analytical Science Advances (ASA). ISSN 2628-5452. 4(7-8), p. 236–243. doi: 10.1002/ansa.202200065. Full text in Research Archive
• Halvorsen, Trine Grønhaug & Reubsaet, Leon (2023). Is this the end of dried blood spots as we know it? Analytical Science Advances (ASA). ISSN 2628-5452. 4(7-8), p. 267–274. doi: 10.1002/ansa.202300006. Full text in Research Archive
• Johannsen, Christina; Mrsa, Ago; Halvorsen, Trine Grønhaug & Reubsaet, Leon (2023). Smart sampling as the “Spot-on” Method for LC-MS protein analysis from dried blood spots. Journal of Separation Science. ISSN 1615-9306. 46(18). doi: 10.1002/jssc.202300394. Full text in Research Archive
• Skaalvik, Tonje Gottenberg; Zhou, Chen; Øiestad, Elisabeth Leere; Hegstad, Solfrid; Trones, Roger & Pedersen-Bjergaard, Stig (2023). Conductive vial electromembrane extraction of opioids from oral fluid. Analytical and Bioanalytical Chemistry. ISSN 1618-2642. 415, p. 5323–5335. doi: 10.1007/s00216-023-04807-3. Full text in Research Archive
• Lauritzen, Fredrik & Gjelstad, Astrid (2023). Trends in dietary supplement use among athletes selected for doping controls. Frontiers in Nutrition. ISSN 2296-861X. 10. doi: 10.3389/fnut.2023.1143187. Full text in Research Archive
• Ellefsen, Christiane Færestrand; Struzek, Anna-Maria; Scherliess, Regina; Hiorth, Marianne & Samuelsen, Anne Berit C. (2023). Preparation of Albatrellus ovinus β-Glucan Microparticles with Dectin-1a Binding Properties. ACS Applied Bio Materials (AABM). ISSN 2576-6422. 6(5), p. 1863–1872. doi: 10.1021/acsabm.3c00071. Full text in Research Archive
• Skogvold, Hanne Bendiksen; Rootwelt, Helge; Reubsaet, Leon; Elgstøen, Katja B. Prestø & Wilson, Steven Ray Haakon (2023). Dried blood spot analysis with liquid chromatography and mass spectrometry: Trends in clinical chemistry. Journal of Separation Science. ISSN 1615-9306. 46(15). doi: 10.1002/jssc.202300210. Full text in Research Archive Show summary

  Dried blood spot samples are simple to prepare and transport, enabling safe andaccessible diagnostics, both locally and globally. We review dried blood spot sam-ples for clinical analysis, focusing on liquid chromatography-mass spectrometryas a versatile measurement tool for these samples. Dried blood spot samplescan provide information for, for example, metabolomics, xenobiotic analysis,and proteomics. Targeted analyses of small molecules are the main applica-tion of dried blood spot samples and liquid chromatography-mass spectrometry,but emerging applications include untargeted metabolomics and proteomics.Applications are highly varied, including analyses related to newborn screen-ing, diagnostics and monitoring of disease progression and treatment effects ofvirtually any disease, as well as studies into the physiology and effects of diet,exercise, xenobiotics, and doping. A range of dried blood spot products andmethods are available, and applied liquid chromatography-mass spectrometryinstrumentation is varied with regard to liquid chromatography column formatsand selectivity. In addition, novel approaches such as on-paper sample prepara-tion (e.g., selective trapping of analytes with paper-immobilized antibodies) aredescribed. We focus on research papers published in the last 5 years.

• Lorenzo-Parodi, Nerea; Kaziur-Cegla, Wiebke; Gjelstad, Astrid & Schmidt, Torsten C. (2023). Liquid-phase microextraction of aromatic amines: hollow fiber–liquid-phase microextraction and parallel artificial liquid membrane extraction comparison. Analytical and Bioanalytical Chemistry. ISSN 1618-2642. 415(9), p. 1765–1776. doi: 10.1007/s00216-023-04579-w. Full text in Research Archive
• Tabani, Hadi; Dorabadizare, Farzaneh & Pedersen-Bjergaard, Stig (2023). Gel electro-membrane extraction: An overview on recent strategies for extraction efficiency enhancement. TrAC. Trends in analytical chemistry. ISSN 0165-9936. 160. doi: 10.1016/j.trac.2023.116990.
• Skaalvik, Tonje Gottenberg; Øiestad, Elisabeth Leere; Pedersen-Bjergaard, Stig & Hegstad, Solfrid (2023). Determination of amphetamine enantiomers in urine by conductive vial electromembrane extraction and ultra-high performance supercritical fluid chromatography tandem mass spectrometry. Drug Testing and Analysis. ISSN 1942-7603. 15, p. 909–918. doi: 10.1002/dta.3487. Full text in Research Archive
• Fu, Yu-ping; Peng, Xi; Zhang, Chao-Wen; Jiang, Quan-Xing; Li, Cen-Yu & Paulsen, Berit Smestad [Show all 21 contributors for this article] (2023). Salvia miltiorrhiza polysaccharide and its related metabolite 5-methoxyindole-3-carboxaldehyde ameliorate experimental colitis by regulating Nrf2/Keap1 signaling pathway. Carbohydrate Polymers. ISSN 0144-8617. 306. doi: 10.1016/j.carbpol.2023.120626. Full text in Research Archive
• Aursnes, Marius; Primdahl, Karoline Gangestad; Liwara, David & Solum, Eirik Johansson (2023). A Modular Strategy for the Synthesis of Dothideopyrones E and F, Secondary Metabolites from an Endolichenic Fungus. Journal of natural products. ISSN 0163-3864. 86(4), p. 804–811. doi: 10.1021/acs.jnatprod.2c00991.
• Senthakumaran, Thulasika; Moen, Aina Elisabeth Fossum; Tannæs, Tone Møller; Endres, Alexander; Brackmann, Stephan Andreas & Rounge, Trine Ballestad [Show all 8 contributors for this article] (2023). Microbial dynamics with CRC progression: a study of the mucosal microbiota at multiple sites in cancers, adenomatous polyps, and healthy controls. European Journal of Clinical Microbiology and Infectious Diseases. ISSN 0934-9723. 42, p. 305–322. doi: 10.1007/s10096-023-04551-7. Full text in Research Archive
• Schüller, Maria; McQuade, Tao Angell-Petersen; Bergh, Marianne Skov-Skov; Pedersen-Bjergaard, Stig & Øiestad, Elisabeth Leere (2023). Determination of tryptamine analogs in whole blood by 96-well electromembrane extraction and UHPLC-MS/MS. Talanta Open. ISSN 2666-8319. 7. doi: 10.1016/j.talo.2022.100171.

View all works in Cristin

• Reubsaet, Leon (2024). Smart Sampling: next generation DBS samplers for LC-MS based protein analysis.
• Wangensteen, Helle (2024). Aloe vera. Store Norske Leksikon (Nettutgaven).
• Wangensteen, Helle (2024). Eterisk olje. Store Norske Leksikon (Nettutgaven).
• Wangensteen, Helle (2024). Akonitin. Store Norske Leksikon (Nettutgaven).
• Reinertsen, Amalie Føreid (2024). Stereoselective Synthesis, Configurational Assignment and Biological Evaluations of the Lipid Mediator RvD2n-3 DPA.
• Reubsaet, Leon (2024). Smart Sampling: next generation DBS samplers for LC-MS based protein analysis.
• de Bourg, Marcus (2024). Synthesis and biological evaluations of epoxy fatty acid mimics.
• Bathen, Mina; Vik, Anders & Hansen, Trond Vidar (2024). Synthetic efforts towards 4S,5S-dihydroxy docosapentaenoic acid.
• Hoel, Håvard & Inngjerdingen, Kari Tvete (2023). Naturmedisiner fra glemmeboken.
• Ulriksen, Emilie Steinbakk; Esam, Nabila; Butt, Hussain Shakeel; Wangensteen, Helle; Hamre, Anne Grethe & Inngjerdingen, Marit [Show all 7 contributors for this article] (2023). Chemical and immunological profiling of polysaccharides from roots of Angelica archangelica L.
• Butt, Hussain Shakeel; Ulriksen, Emilie Steinbakk; Inngjerdingen, Marit; Inngjerdingen, Kari Tvete & Wangensteen, Helle (2023). Structural characterisation of phenolic compounds from the bark of Daphne mezereum L.
• Bada, Lucia; Wangensteen, Helle; Inngjerdingen, Kari Tvete; Gil-Longo, Jose; Quezada, Elias & Vina, Dolores (2023). Antitumoral potential of sub-fractions obtained from Ulex gallii Planch. in human neuroblastoma (SH-SY5Y) and glioblastoma (U-87MG and U-373MG) cell lines.
• Hoel, Håvard & Wangensteen, Helle (2023). Quantification of bitter compounds in (un)traditional preparations of Gentiana purpurea roots.
• Ervik, Karina; Reinertsen, Amalie Føreid & Hansen, Trond Vidar (2023). Synthetic studies towards the specialized pro-resolving mediator RvD5n-3 DPA.
• Ervik, Karina; Reinertsen, Amalie Føreid & Hansen, Trond Vidar (2023). Total synthesis of the specialized pro-resolving mediator RvD5n-3 DPA .
• de Bourg, Marcus; Mohammad, Rawand S. & Vik, Anders (2023). Epoxy fatty acid mimics: A potential treatment for renal failure.
• Christensen, Sofie; Gjelstad, Astrid; Lauritzen, Fredrik & Björnsdottir, Ingunn (2023). Medikalisering av idretten - legemiddelbruk i norsk elite ishockey.
• Sivasambu, Vibitha; Gjelstad, Astrid; Lauritzen, Fredrik & Björnsdottir, Ingunn (2023). Kulturen for bruk av legemidler og kosttilskudd blant utøvere i norsk topphåndball.
• Yusuf, Hoda Khadir; Gjelstad, Astrid; Lauritzen, Fredrik & Björnsdottir, Ingunn (2023). Hvilke legemidler og kosttilskudd benytter idrettsutøvere? Systematisk kartlegging.
• Gjelstad, Astrid (2023). Kan farmasøyter forhindre en dopingsak?
• Skottvoll, Frøydis Sved; Pedersen-Bjergaard, Stig; Mielnik, Michal Marek & Wilson, Steven Ray Haakon (2023). Electromembrane extraction merging with micro-nanotechnology for robust bridging of organ-on-a-chip and mass spectrometry.
• Halvorsen, Trine Grønhaug & Reubsaet, Leon (2023). Next generation dried blood spot samplers for simplified LC-MS/MS analysis of proteins.
• Hansen, Trond Vidar (2023). Biosynthesis, bioactions and biomedical applications of the protectins: New leads in resolution pharmacology .
• Ohrvik, Ane; Inngjerdingen, Kari Tvete; Inngjerdingen, Marit & Kool, Anneleen (2023). Middelaldermedisinen er tilbake. [Radio]. NRK P2. Show summary

  I jakten på nye behandlingsmetoder går forskerne til legebøker fra middelalderen, og henter gamle medisinplanter inn i laboratoriet. Kan disse brukes til å utvikle nye medisiner?

• Ohrvik, Ane; Inngjerdingen, Marit; Inngjerdingen, Kari Tvete & Kool, Anneleen (2023). Svartebøker og gammel folketro inspirerer moderne medisin. Apollon : Forskningsmagasin for Universitetet i Oslo. ISSN 0803-6926. p. 50–57.
• sætre, johan; wolden, Martha; Gottås, André; McQuade, Tao Angell-Petersen; Kjeldsen, Signe Flood & Våtevik, Anne Karine [Show all 12 contributors for this article] (2023). Pharmacokinetic variability of cannabidiol and its metabolites in patients with refractory epilepsy.
• sætre, johan; wolden, Martha; Gottås, Andre; McQuade, Tao Angell-Petersen; Kjeldsen, Signe Flood & Våtevik, Anne [Show all 12 contributors for this article] (2023). Pharmacokinetic variability of cannabidiol in clinical practice.
• Psillakis, Elefteria; Pedersen-Bjergaard, Stig & Ozkan, Sibel (2023). Editorial SI EuSP2022. Advances in Sample Preparation. ISSN 2772-5820. 5. doi: 10.1016/j.sampre.2023.100052.
• Wangensteen, Helle (2023). Gentiana purpurea, a bitter medicinal plant from Norway.
• Halvorsen, Trine Grønhaug & Reubsaet, Leon (2023). Smart samplers for simplified LC-MS/MS analysis of proteins.
• Reubsaet, Leon & Halvorsen, Trine Grønhaug (2023). Smart sampling: next-generation DBS samplers for LC-MS based protein analysis .
• Malerød-Fjeld, Helle & Halvorsen, Trine Grønhaug (2023). The 25th Norwegian symposium on chromatography. Analytical Science Advances (ASA). ISSN 2628-5452. 4(7-8), p. 233–235. doi: 10.1002/ansa.202300035.
• Hansen, Trond Vidar (2023). Biosynthesis, bioactions and biomedical applications of the protectins: New leads in resolution pharmacology.
• Hansen, Trond Vidar (2023). Stereoselective Synthesis of Spesialised Pro-Resolving Mediators (SPMs) Using the sp3-sp3 Negishi Reaction .
• Haatveit, Åsmund Stenvik; Bathen, Mina; Hansen, Trond Vidar & Vik, Anders (2023). Synthetic studies toward 4S,5S-dihydroxy docosapentaenoic acid.
• Bathen, Mina; Haatveit, Åsmund Stenvik; Vik, Anders & Hansen, Trond Vidar (2023). Synthetic studies towards 4S,5S-dihydroxy docosapentaenoic acid .
• Nsowah, Samuel Kwame Opoku; Vik, Anders & Hansen, Trond Vidar (2023). Synthesis of New Analogs of 2-Methoxyestradiol.
• Hansen, Trond Vidar (2023). Stereoselective Synthesis of Sesquiterpenoids Using Organocatalyzed Halocyclization Reactions .
• Wangensteen, Helle (2023). Furanokumariner. Store Norske Leksikon (Nettutgaven).
• Wangensteen, Helle (2023). Kumariner. Store Norske Leksikon (Nettutgaven).
• Smith, V; Hovland, R; Rongved, Pål & Økstad, Ole Andreas (2023). Preclinical development of a novel metallo-β-lactamase inhibitor APC148.
• Bull Tuner, Marius; Kogler, Stian; Hansen, Frederik Andre; Pedersen-Bjergaard, Stig; Røberg-Larsen, Hanne & Wilson, Steven Ray Haakon (2023). Exploring electromembrane extraction and LC-MS for studying liver organoid metabolomics.
• Helleve, Torstein; Hoel, Håvard & Wangensteen, Helle (2023). Oversett av vitskapen: Bitter plante frå folkemedisinen kan ha heilande effekt. [Internet]. https://forskning.no.
• Helleve, Torstein; Hoel, Håvard & Wangensteen, Helle (2023). Forsmådd og bitter folkemedisinplante under lupa. [Internet]. https://titan.uio.no.

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